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Volume 10, Number 10—October 2004
Perspective

Current Epidemiology of Pneumocystis Pneumonia

Alison Morris*†Comments to Author , Jens D. Lundgren‡, Henry Masur§, Peter D. Walzer¶, Debra L. Hanson#, Toni Frederick#, Laurence Huang**, Charles B. Beard††, and Jonathan E. Kaplan#
Author affiliations: *University of Southern California, Los Angeles, California, USA; †University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA; ‡University of Copenhagen, Hvidovre, Denmark; §National Institutes of Health, Bethesda, Maryland, USA; ¶University of Cincinnati, Cincinnati, Ohio, USA; #Centers for Disease Control and Prevention, Atlanta, Georgia, USA; **University of California San Francisco, San Francisco, California, USA; ††Centers for Disease Control and Prevention, Fort Collins, Colorado, USA

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Table 1

Summary of selected studies of Pneumocystis pneumonia in African adultsa

Study (ref) Site Study period No. patients Population Diagnostic sample/method % with 
PCP (n)
Abouya, 1992 (30) Cote d’Ivoire 1989 53 Died while inpatient Autopsy lung tissue/Grocott 8 (4)
Ansari, 2002 (31) Botswana 1997–1998 104 Died while inpatient Autopsy lung tissue/Grocott 11 (11)
Aderaye, 2003 (32) Ethiopia 1996 119 Symptomatic, AFB negative, outpatients Expectorated sputum/IF 11 (13)
Batungwanayo, 1994 (33) Rwanda 1990 111 Symptomatic, AFB negative, outpatients BAL, Tbbx/Methenamine silver 5 (5)
Kamanfu, 1993 (34) Burundi 1991 222 Symptomatic, hospitalized BAL/Giemsa, IF 5 (11)
Malin, 1995 (35) Zimbabwe 1992–1993 64 Symptomatic, hospitalized, 
AFB negative BAL/Methenamine silver, diff-quik, toluidine blue-O 33 (21)
Worodria, 2003 (36) Uganda 1999–2000 83 Symptomatic, hospitalized, 
AFB negative BAL/IF 39 (32)

aAFB, acid-fast bacilli; BAL, bronchoalveolar lavage; IF, immunofluorescence; IS, induced sputum; NPA, nasopharyngeal aspirate.

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