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Volume 10, Number 2—February 2004
THEME ISSUE
2004 SARS Edition
Clinical Studies

Combining Clinical and Epidemiologic Features for Early Recognition of SARS

John A. Jernigan*Comments to Author , Donald E. Low†, and Rita F. Helfand*
Author affiliations: *Centers for Disease Control and Prevention, Atlanta, Georgia, USA; †University of Toronto, Ontario, Canada

Main Article

Table 1

Common clinical features of severe acute respiratory syndrome (SARS)

Clinical feature Common findings with SARS-associated coronavirus infection
Initial symptoms
Nonrespiratory prodrome lasting 2–7 days characterized by one or more of the following:
          Fever
          Rigors
          Headache
          Malaise
          Myalgia
          Diarrhea
Respiratory phase beginning 2–7 days after onset characterized by:
          Nonproductive cough
          Dyspnea
          Absence of upper respiratory symptoms
Laboratory
Normal or low total leukocyte cell count

Lymphopenia

Mildly depressed platelet count

Elevated lactate dehydrogenase levels
Elevated creatine phosphokinase levels
Elevated transaminase levels
Prolonged activated partial thromboplastin time
Radiographic Abnormal chest x-ray in almost all patients by the second week of illness

Main Article

Page created: January 27, 2011
Page updated: January 27, 2011
Page reviewed: January 27, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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