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Volume 10, Number 3—March 2004


Immunofluorescence Assay for Serologic Diagnosis of SARS

Paul K.S. Chan*Comments to Author , King-Cheung Ng*, Rickjason C. W. Chan*, Rebecca K. Y. Lam*, Viola C. Y. Chow*, Mamie Hui*, Alan Wu*, Nelson Lee*, Florence H.Y. Yap*, Frankie W. T. Cheng*, Joseph J. Y. Sung*, and John S. Tam*
Author affiliations: *Faculty of Medicine, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administrative Region, People’s Republic of China

Main Article


Anti-SARS-CoV IgG positive rate and titer according to time of blood sample collectiona

Time of sample collection after onset of fever No. of samples tested No. (%) of samples with anti–SARS IgG antibody detected Anti-SARS IgG antibody titer, range (mode)
1–5 days

6–10 days
12 (34.3)
40–320 (160)
11–15 days
18 (78.3)
40–640 (320)
16–20 days
42 (97.7)
40–2,560 (640)
21–37b days 47 47 (100) 80–5,120 (640)

aSARS, severe acute respiratory syndrome; CoV, coronavirus; IgG, immunoglobulin G; –, not applicable.
bMedian collection time: 22 days; interquartile range: 4 days

Main Article