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Volume 10, Number 5—May 2004


Mass Smallpox Vaccination and Cardiac Deaths, New York City, 1947

Lorna E. Thorpe*†Comments to Author , Farzad Mostashari*, Adam M. Karpati*1, Steven P. Schwartz*, Susan E. Manning*†, Melissa A. Marx*†, and Thomas R. Frieden*
Author affiliations: *New York City Department of Health and Mental Hygiene, New York, New York, USA; †Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table 2

Rate ratio (RR) and 95% confidence interval (CI) of cardiac death rates comparing postvaccination to reference periods,a New York City, March–June, 1946–1948

Outcome Postvaccination period RR (95% CI)
All cardiac deaths (ICD-5 090–095)
April 22–May 5
1.01 (0.96 to 1.07)
50- to 64-year-olds only

1.05 (0.95 to 1.15)
Atherosclerotic cardiac deaths (ICD-5 094)
April 22–May 5
1.06 (0.97 to 1.16)
50- to 64–year-olds only

1.00 (0.86 to 1.15)
Myopericarditis deaths (ICD-5 090, 093)
April 22–May 5
1.00 (0.94 to 1.07)
All deaths
April 22–May 5
1.00 (0.97 to 1.04)
All cardiac deaths (ICD-5 090–095) April 16–May 13 0.99 (0.95 to 1.04)

aAll models are adjusted for long-term temporal and seasonal trends.

Main Article

1At the time of this study, Dr. Karpati was jointly affiliated with the New York City Department of Health and Mental Hygiene and the Centers for Disease Control and Prevention.