Volume 10, Number 9—September 2004
Letter
Vancomycin Heteroresistance in Methicillin-resistant Staphylococcus aureus, Taiwan
Jiun-Ling Wang*, Sung-Pin Tseng*, Po-Ren Hsueh*
, and Keiichi Hiramatsu†
, and Keiichi Hiramatsu†
Table
Characteristics of 21 methicillin-resistant Staphylococcus aureus isolates recovered from two patients with recurrent bacteremiaa
| Designation of isolate | Date of isolation (mo/day/year) | Vancomycin MIC (μg/mL) |
Teicoplanin MIC (μg/mL) |
||||
|---|---|---|---|---|---|---|---|
| Etest |
Broth microdilution |
Agar dilution |
Agar dilution |
||||
| BHI | BHI | MHB | BHI | MHA | MHA | ||
| Patient A (89-y-old man) | |||||||
| A1 | 6/30/2000 | 3 | 2 | 1 | 2 | 2 | 2 |
| A2 | 6/14/2001 | 4 | 3 | 1 | 2 | 2 | 2 |
| A3 | 11/19/2001 | 4 | 4 | 2 | 2 | 2 | 2 |
| A4 | 3/5/2002 | 4 | 3 | 1 | 2 | 2 | 4 |
| A5 | 3/22/2002 | 4 | 3 | 2 | 3 | 2 | 4 |
| A6 | 4/3/2002 | 6 | 5 | 4 | 4 | 2 | 4 |
| A7 | 4/14/2002 | 6 | 5 | 4 | 4 | 3 | 4 |
| A8 | 4/29/2002 | 5 | 4 | 2 | 4 | 3 | 8 |
| A9 | 4/29/2002 | 6 | 3 | 2 | 4 | 3 | 4 |
| A10 | 5/7/2002 | 6 | 4 | 2 | 4 | 2 | 4 |
| Patient B (72-y-old man) | |||||||
| B1 | 4/26/2000 | 3 | 2 | 1 | 2 | 1 | 2 |
| B2 | 5/6/2000 | 4 | 2 | 1 | 2 | 2 | 8 |
| B3 | 5/18/2000 | 6 | 4 | 2 | 4 | 3 | 8 |
| B4 | 5/29/2000 | 5 | 4 | 1 | 4 | 2 | 8 |
| B5 | 6/15/2000 | 6 | 3 | 2 | 4 | 3 | 8 |
| B6 | 6/24/2000 | 8 | 4 | 2 | 4 | 3 | 8 |
| B7 | 7/19/2000 | 8 | 4 | 3 | 5 | 3 | 8 |
| B8 | 1/9/2001 | 4 | 1 | 1 | 2 | 1 | 1 |
| B9 | 1/26/2001 | 4 | 2 | 1 | 2 | 1 | 1 |
| B10 | 3/21/2001 | 3 | 2 | 1 | 2 | 1 | 1 |
| B11 | 4/6/2001 | 4 | 2 | 1 | 2 | 1 | 1 |
| Mu3 | 3 | 3 | 2 | 3 | 2 | – | |
| Mu50 | 10 | 8 | 5 | 8 | 4 | – | |
aBHI, brain heart infusion; MHB, Mueller-Hinton broth; MHA, Mueller-Hinton agar.
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