Volume 11, Number 12—December 2005
Dispatch
Hemolytic Uremic Syndrome Risk and Escherichia coli O157:H7
Boldtsetseg Tserenpuntsag*, Hwa-Gan Chang†
, Perry F. Smith*†, and Dale L. Morse*†
, Perry F. Smith*†, and Dale L. Morse*†
Table 1
Characteristics of hospitalized Escherichia coli O157:H7 patients by HUS case status, New York, 1998–1999*
| Characteristic | Total (N = 238) n (%) | HUS (n = 36) n (%) | Non-HUS (n = 202) n (%) | OR (95% CI) | p value |
|---|---|---|---|---|---|
| Age (y) | |||||
| 0–4 | 34 (14) | 18 (49) | 16 (8) | 4.9 (2.2–11.8) | <0.001 |
| 5–14 | 52 (22) | 6 (17) | 46 (23) | 1.1 (0.4–3.1) | |
| 15–65 | 96 (24) | 6 (17) | 90 (44) | 0.6 (0.2–1.7) | |
| >65 | 56 (40) | 6 (17) | 50 (25) | 1.0 | |
| Sex | |||||
| Female | 147 (62) | 25 (69) | 122 (61) | 1.5 (0.8–3.4) | 0.33 |
| Male | 91 (38) | 11 (31) | 80 (39) | 1.0 | |
| Outcome | |||||
| Dead | 7 (3) | 5 (14) | 2 (1) | 16.1 (2.9–86.8) | 0.001 |
| Alive | 231 (97) | 31 (86) | 200 (99) | 1.0 | |
| Outbreak | |||||
| Yes | 49 (21) | 15 (42) | 34 (17) | 3.6 (1.6–7.5) | 0.01 |
| No | 189 (79) | 21 (58) | 168 (83) | 1.0 | |
| Hospital stay (d) | |||||
| >4 | 121 (51) | 31 (86) | 90 (45) | 7.7 (2.8–20.6) | 0.001 |
| 1–4 | 117 (49) | 5 (14) | 112 (55) | 1.0 | |
| Bloody stool | |||||
| Yes | 203 (85) | 30 (84) | 173 (86) | 0.8 (0.3–2.4) | 0.77 |
| No | 35 (15) | 6 (16) | 29 (14) | 1.0 | |
| Fever | |||||
| Yes | 71 (30) | 19 (53) | 52 (26) | 3.2 (1.6–6.5) | 0.009 |
| No | 167 (70) | 17 (47) | 150 (74) | 1.0 | |
| Vomiting | |||||
| Yes | 96 (40) | 14 (39) | 82 (40) | 0.9 (0.4–1.9) | 0.84 |
| No | 142 (60) | 22 (61) | 120 (60) | 1.0 | |
| Antimicrobial drug use | |||||
| Yes | 89 (37) | 11 (31) | 78 (38) | 0.7 (0.3–1.5) | 0.38 |
| No | 149 (63) | 25 (69) | 124 (62) | 1.0 | |
| Proteinuria at admission | |||||
| Yes | 60 (25) | 23 (64) | 37 (18) | 7.8 (3.6–17.0) | <0.001 |
| No | 178 (75) | 13 (36) | 165 (82) | 1.0 | |
| Hematuria at admission | |||||
| Yes | 80 (34) | 23 (64) | 57 (28) | 4.5 (2.1–9.4) | <0.001 |
| No | 158 (66) | 13 (36) | 145 (72) | 1.0 | |
| Leukocyte count at admission | |||||
| >13,000/μL | 119 (50) | 29 (81) | 90 (44) | 5.2 (2.2–12.3) | <0.001 |
| <13,000/μL | 119 (50) | 7 (19) | 112 (56) | 1.0 | |
| Duration of diarrhea before hospitalization | |||||
| >3 days | 70 (29) | 24 (67) | 46 (23) | 6.7 (3.1–14.6) | <0.001 |
| <3 days | 168 (71) | 12 (33) | 156 (77) | 1.0 | |
*HUS, hemolytic uremic syndrome; OR, odds ratio; CI, confidence interval.
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