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Volume 11, Number 6—June 2005


Global Spread of Vancomycin-resistant Enterococcus faecium from Distinct Nosocomial Genetic Complex

Rob J.L. Willems*Comments to Author , Janetta Top*, Marga van Santen†, D. Ashley Robinson‡, Teresa M. Coque§, Fernando Baquero§, Hajo Grundmann†, and Marc J.M. Bonten*
Author affiliations: *University Medical Center Utrecht, Utrecht, the Netherlands; †National Institute for Public Health and the Environment, Bilthoven, the Netherlands,; ‡New York Medical College, Valhalla, New York, USA; §Hospital Ramon y Cajal, Madrid, Spain

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Table 4

Summary of gene congruence analysis

Gene No. incongruence genes by SH test* Random trees†
adk 1 (atpA) 8 (atpA)
atpA 6 (adk, ddl, gdh, gyd, pstS, purK) 76 (adk)
ddl 6 (adk, atpA, gdh, gyd, pstS, purK) 8 (atpA)
gdh 1 (atpA) 1 (atpA)
gyd 2 (adk, atpA) 0 (atpA)
pstS 6 (adk, atpA, ddl, gdh, gyd, purK) 3 (atpA)
purK 3 (atpA, adk, gyd) 1 (atpA)

*Number of incongruent genes at the p<0.05 level based on a Shimodaira-Hasegawa (SH) test of tree topologies. The incongruent genes are in parentheses.
†Number of random tree topologies out of 100 random trees that are better fit to the gene tree from the most incongruent multilocus sequence typing (MLST) gene. The most incongruent MLST gene is given in parentheses.

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