Volume 11, Number 6—June 2005
Research
Emergence and Spread of Streptococcus pneumoniae with erm(B) and mef(A) Resistance
David J. Farrell*
, Stephen G. Jenkins†, Steven D. Brown‡, Manish Patel§, Bruce S. Lavin§, and Keith P. Klugman¶#
, Stephen G. Jenkins†, Steven D. Brown‡, Manish Patel§, Bruce S. Lavin§, and Keith P. Klugman¶#
Table 6
Lineage by country of 366 dual erm(B)+mef(A) erythromycin-resistant Streptococcus pneumoniae isolates collected during the PROTEKT global study (1999–2003)
| Country | No. isolates | Clonal complex |
|||
|---|---|---|---|---|---|
| CC 271 | CC 242 | CC 81 | None* | ||
| Australia | 6 | 6 | – | – | – |
| Brazil | 2 | 2 | – | – | – |
| Canada | 4 | 4 | – | – | – |
| China | 13 | 12 | – | – | 1 |
| France | 3 | 1 | – | – | 2 |
| Germany | 1 | 1 | – | – | – |
| Hong Kong | 2 | 2 | – | – | – |
| Hungary | 2 | 2 | – | – | – |
| Italy | 2 | 2 | – | – | – |
| Japan | 44 | 12 | 16 | 1 | 15† |
| Mexico | 6 | 4 | – | – | 2 |
| South Africa | 129 | 116 | 9 | 2 | 2 |
| South Korea | 111 | 102 | – | 6 | 3 |
| Taiwan | 5 | 3 | – | – | 2 |
| United Kingdom | 1 | 1 | – | – | – |
| United States | 35 | 35 | – | – | – |
| Total, n (%) | 366 (100) | 305 (83.3) | 25 (6.8) | 9 (2.5) | 27 (7.4) |
*No clonal lineage found except for 2 isolates (ST 1467) and 1 isolate (ST 1452), which were clonally related (CC 1467).
†8 isolates were clonally related (ST 1426).
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