Volume 11, Number 6—June 2005
Research
Emergence and Spread of Streptococcus pneumoniae with erm(B) and mef(A) Resistance
, Stephen G. Jenkins†, Steven D. Brown‡, Manish Patel§, Bruce S. Lavin§, and Keith P. Klugman¶#
Table 1
Geographic distribution by year of Streptococcus pneumoniae collected from years 1 to 3 of the PROTEKT US study with both erm(B)- and mef(A)-encoded macrolide resistance among genotyped erythromycin-resistant isolates
| US region* | No. erm(B)+mef(A)–positive/no. erythromycin-resistant (%) |
|||
|---|---|---|---|---|
| Year 1 | Year 2 | Year 3 | Years 1–3 combined | |
| North-Central | 121/667 (18.1) | 117/626 (18.7) | 176/735 (23.9) | 414/2,028 (20.4) |
| Northeast | 88/985 (8.9) | 96/771 (12.5) | 140/900 (15.6) | 324/2,656 (12.2) |
| Northwest | 8/98 (8.2) | 18/119 (15.1) | 26/125 (20.8) | 52/342 (15.2) |
| South-Central | 23/561 (4.1) | 36/463 (7.8) | 80/667 (12.0) | 139/1,691 (8.2) |
| Southeast | 29/427 (6.8) | 31/481 (6.4) | 49/475 (10.3) | 109/1,383 (7.9) |
| Southwest | 35/395 (8.9) | 37/333 (11.1) | 49/275 (17.8) | 121/1,003 (12.1) |
| Total | 304/3,133 (9.7) | 335/2,793 (12.0) | 520/3,177 (16.4) | 1,159/9,103 (12.7) |
*North-Central = Illinois, Iowa, Kansas, Minnesota, Missouri, Nebraska, North Dakota, South Dakota, Wisconsin; Northeast = Connecticut, Delaware, Indiana, Maryland, Massachusetts, Michigan, New Jersey, New York, Ohio, Pennsylvania, Rhode Island, Vermont, Washington DC; Northwest = Alaska, Idaho, Montana, Oregon, Washington, Wyoming; South-Central = Alabama, Arkansas, Louisiana, Oklahoma, Tennessee, Texas; Southeast = Florida, Georgia, Kentucky, North Carolina, Puerto Rico, South Carolina, Virginia, West Virginia; Southwest = Arizona, California, Colorado, Nevada, New Mexico, Utah.