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Volume 11, Number 9—September 2005

Dengue Virus Type 3, Brazil, 2002

Rita Maria Ribeiro Nogueira*Comments to Author , Hermann Gonçalves Schatzmayr*, Ana Maria Bispo de Filippis*, Flávia Barreto dos Santos*, Rivaldo Venâncio da Cunha†, Janice Oliveira Coelho‡, Luiz José de Souza§, Flávia Ramos Guimarães*, Eliane Saraiva Machado de Araújo*, Thatiane Santos De Simone*, Meri Baran¶, Gualberto Teixeira#, and Marize Pereira Miagostovich*
Author affiliations: *Instituto Oswaldo Cruz, Rio de Janeiro, Brasil; †Faculdade de Medicina de Mato Grosso do Sul, Campo Grande, Brazil; ‡Instituto de Pesquisa Clínica Evandro Chagas, Rio de Janeiro, Brazil; §Centro de Referencia de Dengue, Campos dos Goytacazes, Brazil; ¶Secretaria Municipal de Saúde do Rio de Janeiro, Rio de Janeiro, Brazil; #Secretaria de Saúde do Estado do Rio de Janeiro, Rio de Janeiro, Brazil

Main Article

Table 2

Investigation of suspected fatal dengue cases according to available clinical samples*

Clinical specimen RT-PCR positive/studied (%) Virus isolation positive/studied (%) Serotype detected MAC-ELISA positive/studied Immunohistochemistry positive/studied Confirmed cases/studied cases (%)
Serum 15/42 4/38 15 DENV-3 18/42 ND 26/42 (61.9)
CSF 1/ 2 0/2 1 DENV-3 0/2 ND 1/2
Fresh tissues 17/59 2/59 17 DENV-3 ND ND 17/59(28.8)
Formalin-fixed and paraffin embedded tissues ND ND 0 0 23/48 23/48 (47.9)
Total 33/103 (32.0) 6/99 (6.0) 33 DENV-3 18/44 (40.9) 23/48 (47.9) 40/62† (64.5)

*RT-PCR, reverse transcriptase–polymerase chain reaction; MAC-ELISA, immunoglobulin M antigen capture enzyme-linked immunosorbent assay; DENV, dengue virus; IgG, immunoglobulin G; ND, not done; CSF cerebrospinal fluid.
†Total of confirmed fatal cases by any method/total of fatal cases studied.

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Page created: April 23, 2012
Page updated: April 23, 2012
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