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Volume 12, Number 1—January 2006
Research

Estimating Influenza Hospitalizations among Children

Carlos G. Grijalva*, Allen S. Craig*†, William D. Dupont*, Carolyn B. Bridges‡, Stephanie J. Schrag‡, Marika K. Iwane‡, William Schaffner*, Kathryn M. Edwards*, and Marie R. Griffin*Comments to Author 
Author affiliations: *Vanderbilt University School of Medicine; Nashville, Tennessee, USA; †Tennessee Department of Health, Nashville, Tennessee, USA; ‡Centers for Disease Control and Prevention, Atlanta, Georgia, USA

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Figure 1

Capture-recapture estimation using data from 2 independent sources. The first surveillance system (New Vaccine Surveillance Network [NVSN]) captured n1 cases. The second system (Emerging Infections Program [EIP]) captured n2 cases, including m2 cases already captured by NVSN (matched cases). The Peterson estimator of N (total cases) is [[INLINEGRAPHIC('05-0308-M1')]]= n1 × n2/m2. The Peterson estimate implies that the estimated number of cases missed by both systems (z) = (b × c)/(a); where b is

Figure 1. Capture-recapture estimation using data from 2 independent sources. The first surveillance system (New Vaccine Surveillance Network [NVSN]) captured n1 cases. The second system (Emerging Infections Program [EIP]) captured n2 cases, including m2 cases already captured by NVSN (matched cases). The Peterson estimator of N (total cases) is

formula image
= n1 × n2/m2. The Peterson estimate implies that the estimated number of cases missed by both systems (z) = (b × c)/(a); where b is the number of enrolled cases by the EIP only, c is the number of enrolled cases by the NVSN only, and a is the number of matched cases (m2) (2125).

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