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Volume 12, Number 12—December 2006
Synopsis

Review of Bats and SARS

Lin-Fa Wang*Comments to Author , Zhengli Shi†, Shuyi Zhang‡§, Hume E. Field¶, Peter Daszak#, and Bryan T. Eaton*
Author affiliations: *Australian Animal Health Laboratory, Geelong, Victoria, Australia; †Wuhan Institute of Virology of Chinese Academy of Sciences, Wuhan, People’s Republic of China; ‡Institute of Zoology of Chinese Academy of Sciences, Beijing, People’s Republic of China; §East China Normal University, Shanghai, People’s Republic of China; ¶Department of Primary Industries and Fisheries, Brisbane, Queensland, Australia; #Consortium for Conservation Medicine, New York, New York USA

Main Article

Table 2

Coronaviruses detected in different species of bats

Viruses
Bat species Location of detection
(People’s Republic of China) Reference
Group* Name/strain
G1 Bat-CoV HKU2 Rhinolophus sinicus Hong Kong (32)
Bat-CoV HKU6 Myotis ricketti Hong Kong (32)
Bat-CoV HKU7 Miniopterus magnater Hong Kong (32)
Bat-CoV HKU8 Miniopterus pusillusM. magnaterMiniopterus schreibersii Hong Kong (28,32)
BtCoV/701/05 Myotis ricketti Anhui, Yunnan, Guangdong (33)
BtCoV/821/05 Myotis ricketti Jiangxi, Guangxi (33)
BtCOV/821/05 Scolophlus kuhlii Hainan (33)
BtCoV/970/06 Rhinolophus pearsoniRhinolophus ferrumequinum Shandong (33)
BtCoV/A773/05 M. schreibersii Fujian (33)
BtCoV/A011/05 M. schreibersii Anhui, Fujian, Guangxi (33)
G2b Rp3 R. pearsoni Guangxi (30)
Rm1 (BtCoV/279/04) Rhinolophus macrotis Hubei (30)
Rf1 (BtCoV/273/04) R. ferrumequinum Hubei (30)
Bat-SARS-CoV HKU3 R. sinicus Hong Kong (31,32)
BtCoV/A1018/06 R. sinicus Shandong (33)
BtCoV/279/04 R, macrotis Hubei (33)
BtCoV/273/04 R. ferrumequinum Hubei (33)
G2c Bat-CoV HKU4 Tylonycteris pachypus Hong Kong (32)
Bat-CoV HKU5 Pipistrellus abramus Hong Kong (32)
BtCoV/133/05 T. pachypus Guangdong (33)
BtCoV/434/05 Pipistrellus pipistrellus Hainan (33)
BtCoV/355/05 P. abramusR. ferrumequinum Anhui, Henan, Sichuan (33)

*Group 2 was subdivided as in (32). A different classification was used in (33), in which G2b and G2c were designated G4 and G5, respectively.

*Group 2 was subdivided as in (32). A different classification was used in (33), in which G2b and G2c were designated G4 and G5, respectively.

*Group 2 was subdivided as in (32). A different classification was used in (33), in which G2b and G2c were designated G4 and G5, respectively.

Main Article

References
  1. Peiris  JSM, Guan  Y, Yuen  KY. Severe acute respiratory syndrome. Nat Med. 2004;10:S8897. DOIPubMedGoogle Scholar
  2. Liang  G, Chen  QX, Xu  JG, Liu  YF, Lim  W, Peiris  JSM, Laboratory diagnosis of four recent sporadic cases of community-acquired SARS, Guangdong Province, China. Emerg Infect Dis. 2004;10:177481.PubMedGoogle Scholar
  3. Song  HD, Tu  CC, Zhang  GW, Wang  SY, Zheng  K, Lei  LC, Cross-host evolution of severe acute respiratory syndrome coronavirus in palm civet and human. Proc Natl Acad Sci U S A. 2005;102:24305. DOIPubMedGoogle Scholar
  4. Rota  PA, Oberste  MS, Monroe  SS, Nix  WA, Campagnoli  R, Icenogle  JP, Characterization of a novel coronavirus associated with severe acute respiratory syndrome. Science. 2003;300:13949. DOIPubMedGoogle Scholar
  5. Marra  MA, Jones  SJ, Astell  CR, Holt  RA, Brooks-Wilson  A, Butterfield  YS, The genome sequence of the SARS-associated coronavirus. Science. 2003;300:1399404. DOIPubMedGoogle Scholar
  6. Ksiazek  TG, Erdman  D, Goldsmith  CS, Zaki  SR, Peret  T, Emery  S, A novel coronavirus associated with severe acute respiratory syndrome. N Engl J Med. 2003;348:195366. DOIPubMedGoogle Scholar
  7. Xu  RH, He  JF, Evans  MR, Peng  GW, Field  HE, Yu  DW, Epidemiologic clues to SARS origin in China. Emerg Infect Dis. 2004;10:10307.PubMedGoogle Scholar
  8. Centers for Disease Control and Prevention. Prevalence of IgG antibody to SARS-associated coronavirus in animal traders—Guangdong Province, China, 2003. MMWR Morb Mortal Wkly Rep. 2003;52:9867.PubMedGoogle Scholar
  9. Guan  Y, Zheng  BJ, He  YQ, Liu  XL, Zhuang  ZX, Cheung  CL, Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China. Science. 2003;302:2769. DOIPubMedGoogle Scholar
  10. Chinese SARS Molecular Epidemiology Consortium. Molecular evolution of the SARS coronavirus during the course of the SARS epidemic in China. Science. 2004;303:16669. DOIPubMedGoogle Scholar
  11. Wu  D, Tu  C, Xin  C, Xuan  H, Meng  Q, Liu  Y, Civets are equally susceptible to experimental infection by two different severe acute respiratory syndrome coronavirus isolates. J Virol. 2005;79:26205. DOIPubMedGoogle Scholar
  12. Fouchier  RA, Kuiken  T, Schutten  M, Van Amerongen  G, van Doornum  GJ, van den Hoogen  BG, Aetiology: Koch's postulates fulfilled for SARS virus. Nature. 2003;423:240. DOIPubMedGoogle Scholar
  13. Qin  C, Wang  JW, Wei  Q, She  MP, Marasco  WA, Jiang  H, An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus. J Pathol. 2005;206:2519. DOIPubMedGoogle Scholar
  14. Li  BJ, Tang  Q, Cheng  D, Qin  C, Xie  FY, Wei  Q, Using siRNA in prophylactic and therapeutic regimens against SARS coronavirus in Rhesus macaque. Nat Med. 2005;11:94451.PubMedGoogle Scholar
  15. Bukreyev  A, Lamirande  EW, Buchholz  UJ, Vogel  LN, Elkins  WR, St Claire  M, Mucosal immunisation of African green monkeys (Cercopithecus aethiops) with an attenuated parainfluenza virus expressing the SARS coronavirus spike protein for the prevention of SARS. Lancet. 2004;363:21227. DOIPubMedGoogle Scholar
  16. Martina  BE, Haagmans  BL, Kuiken  T, Fouchier  RA, Rimmelzwaan  GF, van Amerongen  G, Virology: SARS virus infection of cats and ferrets. Nature. 2003;425:915. DOIPubMedGoogle Scholar
  17. Roberts  A, Vogel  L, Guarner  J, Hayes  N, Murphy  B, Zaki  S, Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters. J Virol. 2005;79:50311. DOIPubMedGoogle Scholar
  18. Liang  L, He  C, Lei  M, Li  S, Hao  Y, Zhu  H, Pathology of guinea pigs experimentally infected with a novel reovirus and coronavirus isolated from SARS patients. DNA Cell Biol. 2005;24:48590. DOIPubMedGoogle Scholar
  19. Roberts  A, Paddock  C, Vogel  L, Butter  E, Zaki  S, Subbarao  K. Aged BALB/c mice as a model for increased severity of severe acute respiratory syndrome in elderly humans. J Virol. 2005;79:58338. DOIPubMedGoogle Scholar
  20. Subbarao  K, Mcauliffe  J, Vogel  L, Fahle  G, Fischer  S, Tatti  K, Prior infection and passive transfer of neutralizing antibody prevent replication of severe acute respiratory syndrome coronavirus in the respiratory tract of mice. J Virol. 2004;78:35727. DOIPubMedGoogle Scholar
  21. Chen  W, Yan  M, Yang  L, Ding  B, He  B, Wang  YZ, SARS-associated coronavirus transmitted from human to pig. Emerg Infect Dis. 2005;11:4468.PubMedGoogle Scholar
  22. Weingartl  HM, Copps  J, Drebot  MA, Marszal  P, Smith  G, Gren  J, Susceptibility of pigs and chickens to SARS coronavirus. Emerg Infect Dis. 2004;10:17984.PubMedGoogle Scholar
  23. Ng  SKC. Possible role of an animal vector in the SARS outbreak at Amoy Gardens. Lancet. 2003;362:5702. DOIPubMedGoogle Scholar
  24. Swayne  DE, Suarez  DL, Spackman  E, Tumpey  TM, Beck  JR, Erdman  D, Domestic poultry and SARS coronavirus, southern China. Emerg Infect Dis. 2004;10:9146.PubMedGoogle Scholar
  25. Wang  M, Yan  M, Xu  H, Liang  W, Kan  B, Zheng  B, SARS-CoV infection in a restaurant from palm civet. Emerg Infect Dis. 2005;11:18605.PubMedGoogle Scholar
  26. Tu  C, Crameri  G, Kong  X, Chen  J, Sun  Y, Yu  M, Antibodies to SARS coronavirus in civets. Emerg Infect Dis. 2004;10:22448.PubMedGoogle Scholar
  27. Kan  B, Wang  M, Jing  H, Xu  H, Jiang  X, Yan  M, Molecular evolution analysis and geographic investigation of severe acute respiratory syndrome coronavirus-like virus in palm civets at an animal market and on farms. J Virol. 2005;79:11892900. DOIPubMedGoogle Scholar
  28. Poon  LLM, Chu  DKW, Chan  KH, Wong  OK, Ellis  TM, Leung  YHC, Identification of a novel coronavirus in bats. J Virol. 2005;79:20019. DOIPubMedGoogle Scholar
  29. Hudson  PJ, Rizzoli  A, Grenfell  BT, Heesterbeek  H, Dobson  AP. The ecology of wildlife diseases. Oxford (UK): Oxford University Press; 2002.
  30. Li  W, Shi  Z, Yu  M, Ren  W, Smith  C, Epstein  JH, Bats are natural reservoirs of SARS-like coronaviruses. Science. 2005;310:6769. DOIPubMedGoogle Scholar
  31. Lau  SKP, Woo  PCY, Li  KSM, Huang  Y, Tsoi  HW, Wong  BHL, Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats. Proc Natl Acad Sci U S A. 2005;102:140405. DOIPubMedGoogle Scholar
  32. Woo  PC, Lau  SK, Li  KS, Poon  RW, Wong  BH, Tsoi  HW, Molecular diversity of coronaviruses in bats. Virology. 2006;351:1807. DOIPubMedGoogle Scholar
  33. Tang  XC, Zhang  JX, Zhang  SY, Wang  P, Fan  XH, Li  LF, Prevalence and genetic diversity of coronaviruses in bats from China. J Virol. 2006;80:748190. DOIPubMedGoogle Scholar
  34. Childs  JE. Zoonotic viruses of wildlife: hither from yon. Arch Virol Suppl. 2004;18:111.PubMedGoogle Scholar
  35. Li  W, Wong  S-K, Li  F, Kuhn  JH, Huang  I-C, Choe  H, Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions. J Virol. 2006;80:42119. DOIPubMedGoogle Scholar
  36. Calisher  CH, Childs  JE, Field  HE, Holmes  KV, Schountz  T. Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev. 2006;19:53145. DOIPubMedGoogle Scholar
  37. Breed  AC, Field  HE, Epstein  JH, Daszak  P. Emerging henipaviruses and flying foxes–conservation and management perspectives. Biol Conserv. 2006;131:21120. DOIGoogle Scholar
  38. Mackenzie  JS, Field  HE. Emerging encephalitogenic viruses: lyssaviruses and henipaviruses transmitted by frugivorous bats. Arch Virol Suppl. 2004;18:97111.PubMedGoogle Scholar
  39. Harris  SL, Brookes  SM, Jones  G, Huston  AM, Racey  PA, Aegerter  J, European bat lyssaviruses: distribution, prevalence and implications for conservation. Biol Conserv. 2006;131:193210. DOIGoogle Scholar
  40. Cleaveland  S, Laurenson  MK, Taylor  LH. Diseases of humans and their domestic mammals: pathogen characteristics, host range and the risk of emergence. Philos Trans R Soc Lond B Biol Sci. 2001;356:9919. DOIPubMedGoogle Scholar

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Page created: October 04, 2011
Page updated: October 04, 2011
Page reviewed: October 04, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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