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Volume 12, Number 2—February 2006


Rickettsial Infections and Fever, Vientiane, Laos

Simaly Phongmany*, Jean-Marc Rolain†, Rattanaphone Phetsouvanh*, Stuart D. Blacksell*‡§, Vimone Soukkhaseum*, Bouachanh Rasachack*, Khamphong Phiasakha*, Surn Soukkhaseum*, Khamthavi Frichithavong*, Vang Chu*, Valy Keolouangkhot*¶, Bertrand Martinez-Aussel*#, Ko Chang*, Chirapha Darasavath*, Oudayvone Rattanavong*, Siho Sisouphone*, Mayfong Mayxay*#, Sisouphane Vidamaly*¶, Philippe Parola†, Chanpheng Thammavong*, Mayboun Heuangvongsy*, Bounkong Syhavong*, Didier Raoult†, Nicholas J. White*‡§, and Paul N. Newton*‡Comments to Author 
Author affiliations: *Mahosot Hospital, Vientiane, Laos; †Université de la Méditerranée, Marseille, France; ‡University of Oxford, Oxford, United Kingdom; §Mahidol University, Bangkok, Thailand; #National University of Laos, Vientiane, Laos; ¶Francophone Institute for Tropical Medicine, Vientiane, Laos

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Table 2

Clinical features of patients with serologic evidence for acute spotted fever rickettsioses admitted to Mahosot Hospital*

Patient no. Age (y), sex Occupation Month of onset of illness Clinical features Home
45 30, male Construction worker March 18-day fever, myalgia, nausea, epistaxis, vomiting, abdominal pain, petechial rash on trunk and legs; liver and spleen not palpable; treated with ampicillin and gentamicin Vientiane City
72 35, female Teacher April 13-day fever, chills, headache, nausea, myalgia, vomiting, conjunctival suffusion, dyspnea, 12-cm liver; treated with ofloxacin Vientiane City
86 25, male Health worker May 11-day fever, headache, nausea, vomiting, abdominal pain, 10-cm liver Vientiane City
114 18, male Student June 14-day fever, chill, headache, arthralgia, myalgia, rash developed 2 days after admission, 12-cm liver; treated with ofloxacin Vientiane Province
198 50, male Government official September 24-day fever, headache, arthralgia, myalgia, vertigo, epistaxis, diarrhea; abdominal CT suggested hepatic carcinoma; no antimicrobial drug Xieng Khuang Province
237 64, male Government official September 21-day fever, myalgia, arthralgia, abdominal pain, sore throat, cough, dyspnea; chest exam abnormal Vientiane City
290 24, female Construction worker March 7-day fever, headache, vomiting, myalgia, unproductive cough, diarrhea; treated with doxycycline Vientiane City
362 23, female Student June 10-day fever, myalgia, headache, conjunctival suffusion, 8-cm liver; treated with doxycycline Vientiane City
297 43, female Housewife March 14-day fever, headache, jaundice, RUQ pain, myalgia, 8-cm hepatomegaly; abdominal CT suggested tumor of intrahepatic bile ducts (cholangiocarcinoma?); treated with ampicillin and gentamicin Xieng Khuang Province
55 34, female Housewife April 7-day fever, chills, headache, myalgia, diarrhea, abdominal pain, nausea, vomiting, rash on arms and abdomen; treated with oral chloramphenicol Vientiane Province
239 46, male Merchant November 6-day fever, headache, myalgia, arthralgia, nausea, abdominal pain, diarrhea, dyspnea, dry cough, and sore throat; treated with doxycycline Vientiane City

*CT, computed tomographic scan; RUQ, right upper quadrant.

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