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Volume 12, Number 6—June 2006


Cowpox Virus Transmission from Rats to Monkeys, the Netherlands

Byron E.E. Martina*, Gerard van Doornum*, Gerry M. Dorrestein†, Hubert G.M. Niesters*, Koert J. Stittelaar*, Marno A.B.I. Wolters‡, Hester G.H. van Bolhuis*, and Albert D.M.E. Osterhaus*Comments to Author 
Author affiliations: *Erasmus Medical Center Rotterdam, Rotterdam, the Netherlands; †Utrecht University, Utrecht, the Netherlands; ‡AAP Sanctuary for Exotic Animals, Almere, the Netherlands

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Results for animals tested for cowpox virus infection, the Netherlands, 2003*

Animal tested VNT ELISA Virus isolation PCR
Barbary macaque (Macaca sylvanus) 9/16 9/16 ND ND
Pig-tailed macaque (M. nemestrina) 2/2 2/2 ND ND
Squirrel monkey (Saimiri sciureus) 0/2 0/2 ND ND
Japanese macaque (M. fuscata) 1/2 1/2 ND ND
Cynomolgus macaque (M. fascicularis) 3/6 4/6 ND ND
Hamadryas baboon (Papio hamadryas) 0/2 0/2 ND ND
Rhesus macaque (M. mulatta) 1/4 2/4 ND ND
Vervet (Cercopithecus aethiops) 0/1 0/1 ND ND
Domestic cat (Felis catus) 1/4 3/4 0/4 0/4
Red squirrel (Sciurus vulgaris) 0/2 0/2 0/2 0/2
Prairie dog (Cynomys ludovicianus) 0/6 0/6 0/6 0/6
Wood mouse (Apodemus sylvaticus) 0/32 2/32 0/32 0/32
Brown rat (Rattus norvegicus) ND 11/34 16/28 19/34

*Values are no. positive/no. tested. VNT, virus neutralization test; ELISA, enzyme-linked immunosorbent assay; PCR, polymerase chain reaction, ND, not determined.

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