Volume 12, Number 6—June 2006
Research
Genetic Divergence of Toxoplasma gondii Strains Associated with Ocular Toxoplasmosis, Brazil
Table
Genotypes of Toxoplasma gondii in human ocular toxoplasmosis samples from Brazil*
| Strain name | Type of sample | Source | Locus |
|||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 5´-SAG2† | 3´-SAG2‡ | BTUB§ | SAG3 | GRA6 | Genotype | Reference¶ | Location | |||
| ENT | C# | Human | 1** | 1 | 1,1 | 1 | 1 | I | ENT | F |
| RH | C | Human | 1 | 1 | 1,1 | 1 | 1 | I | RH | USA-OH |
| GT1 | C | Goat | 1 | 1 | 1,1 | 1 | 1 | I | GT1 | USA-MD |
| VEL | C | Human | 1 | 1 | 1,1 | 1 | 1 | I | VEL | USA-CA |
| Me49 | C | Sheep | 1 | 2 | 2,2 | 2 | 2 | II | Me49 | USA-CA |
| DEG | C | Human | 1 | 2 | 2,2 | 2 | 2 | II | DEG | F |
| PIH | C | Human | 1 | 2 | 2,2 | 2 | 2 | II | PIH | USA-CA |
| CTG | C | Cat | 2 | 1 | 2,1 | 3 | 3 | III | CTG | USA-NIH |
| STRL | C | Human | 2 | 1 | 2,1 | 3 | 3 | III | STRL | USA-CA |
| VEG | C | Human | 2 | 1 | 2,1 | 3 | 3 | III | VEG | USA-CA |
| CAST | C | Human | 1 | 1 | 1,1 | 1 | 1 | I | CAST | USA-CA |
| COUG | C | Cougar | 1 | 2 | 2,2 | 3 | 2 | I/II/III | COUG | CAN-BC |
| MAS | C | Human | 1 | 1 | 2,1 | 3 | 3 | I/III | MAS | F |
| PBR | C | Dog | 1 | 1 | 1,1 | 3 | 3 | I/III | MG1 | SP |
| D3 | C | Dog | 1 | 1 | 2,1 | 3 | 3 | I/III | MG2 | MG |
| CH1 | C | Chicken | 2 | 1 | 2,1 | 3 | 3 | III | MG3 | MG |
| CH2 | C | Chicken | 2 | 1 | 2,1 | 3 | 3 | III | MG4 | MG |
| EFP | C | Human | 1 | 1 | 2,1 | 3 | 3 | I/III | MG5 | MG |
| SAF | C | Human | 1 | 1 | 2,1 | 3 | 3 | I/III | MG6 | MG |
| 6T | A†† | Porcine | 1 | 1 | 2,1 | 3 | 3 | I/III | P1 | EC |
| 7T | A | Porcine | 1 | 1 | 2,1 | 3 | 3 | I/III | P2 | EC |
| 8T | A | Porcine | 1 | 1 | 2,1 | 3 | 2 | I/II/III | P3 | EC |
| 9T | A | Porcine | 1 | 1 | 2,1 | 3 | 3 | I/III | P4 | EC |
| 2147 | Cl‡‡ | Recurrent ocular | 1 | 1 | 1,1 | 2 | 1 | I/II | ER1 | ER |
| 2324 | Cl | Acute ocular | 1 | 1 | 1,1 | 2 | 1 | I/II | ER2 | ER |
| 2296 | Cl | Acute ocular | 1 | 1 | 1,1 | 2 | 1 | I/II | ER3 | ER |
| 2323 | Cl | Acute ocular | 1 | 1 | 1,1 | 2 | 1 | I/II | ER4 | EC |
| 2434 | Cl | Recurrent ocular | 1 | 1 | 1,1 | 2 | 1 | I/II | ER5 | ER |
| 2325 | Cl | Acute ocular | 1 | 1 | 1,1 | 3 | 1 | I/III | ER6 | ER |
| 2566 | Cl | Recurrent ocular | 1 | 2 | 1,1 | 3 | –§§ | I/II/III | ER7 | ER |
| 2583 | Cl | Acute ocular | 1 | 1 | 1,1 | 1 | – | I | ER8 | ER |
| 2612 | Cl | Recurrent ocular | 1 | – | 1,1 | 2 | – | I/II | ER9 | ER |
| 2670 | Cl | Recurrent ocular | 1 | – | 1,1 | 2 | – | I/II | ER10 | EC |
| 2728 | Cl | Acute ocular | 1 | 1 | 1,1 | 1 | – | I | ER11 | EC |
| 2694 | Cl | Outbreak | 1 | 2 | 1,1 | 3 | – | I/II/III | SV | SV |
| 2712 | Cl | Outbreak | 1 | – | 1,1 | 2 | – | I/II | AG1 | AG |
| 2717 | Cl | Outbreak | 1 | – | 1,1 | 1 | – | I | AG2 | AG |
| 2719 | Cl | Outbreak | 1 | 1 | 1,1 | 2 | 1 | I/II | AG3 | AG |
*C, culture; A, animal; Cl, clinical; F, France; CA, California; NIH, National Institutes of Health; CAN-BC, British Columbia, Canada; SP, São Paulo; MG, Belo Horizonte, Minas Gerais; EC, Erechim City; ER, Erechim region; SV, Santa Vitttoria do Palmar; AG, Agronomica.
†Genotypes I and II are the same.
‡Genotypes I and III are the same.
§Alleles represent BsiEI and TaqI, respectively.
¶As referred in figures.
#Culture strains used as reference.
**Alleles defined by pattern in type I strain = 1, second allele = 2; allele 3 is defined by the presence of a second biallelic polymorphism.
††Meat tissue samples, primary source.
‡‡Human ocular toxoplasmosis.
§§Refers to negative amplification product.