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Volume 12, Number 9—September 2006
Dispatch

Multidrug-resistant Mycobacterium tuberculosis, Bangui, Central African Republic

Laurent Nouvel*, Eric Kassa-Kelembho†, Tiago Dos Vultos*, Germain Zandanga†, Jean Rauzier*, Carmen Lafoz‡, Carlos Martin‡, Jesus Blazquez§, Antoine Talarmin†, and Brigitte Gicquel*Comments to Author 
Author affiliations: *Institut Pasteur, Paris, France; †Institut Pasteur, Bangui, Central African Republic; ‡Universidad de Zaragoza, Zaragoza, Spain; §Centro Nacional de Biotecnología, Madrid, Spain

Main Article

Table

rpoB mutations observed in strains of cluster E and F*

Cluster No. ATB rpoB mutT1
E 7 R/I/E Asp GAC 516 Val GTC Val GTC 265 Val GTA
E 8 R/I/S Asp GAC 516 Val GTC Val GTC 265 Val GTA
E 9 R/I/E/S Asp GAC 516 Val GTC Val GTC 265 Val GTA
E 10 R/I/S His CAC 526 Arg CGC Val GTC 265 Val GTA
E 11 R/I/E/S His CAC 526 Arg CGC Val GTC 265 Val GTA
E 45 R/I/E/S His CAC 526 Arg CGC Val GTC 265 Val GTA
E 46 R/I/E/S His CAC 526 Arg CGC ND
E 12 R/I/E/S His CAC 526 Asp GAC Val GTC 265 Val GTA
E 13 R/I/E His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 14 R/I/E/S His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 15 R/I/E His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 16 R/I/S His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 17 R/I/E/S His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 18 R/I His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 19 R/I/E His CAC 526 Tyr TAC Val GTC 265 Val GTA
E 47 R/I/E/S His CAC 526 Tyr TAC ND
E 20 R/I/E Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 21 R/I/E/S Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 22 R/I/E/S Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 23 R/I/E/S Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 24 R/I/E Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 44 R/I/E/S Ser TCG 531 Leu TTG Val GTC 265 Val GTA
F 27 R/I/S Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 49 R/I/E/S Ser TCG 531 Leu TTG Val GTC 265 Val GTA
E 50 R/I/E/S Ser TCG 531 Leu TTG ND
E 48 R/I Leu CTG 533 Pro CCG ND

*ATB, antibiogram results, indicates strains resistant to rifampin (R), isoniazid (I), ethambutol (E), and streptomycin (S); ND, not determined.

Main Article

Page created: November 18, 2011
Page updated: November 18, 2011
Page reviewed: November 18, 2011
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