Volume 14, Number 12—December 2008
Letter
Antibodies against Rickettsia spp. in Hunters, Germany
Table
Positive immunofluorescence assay results for antigens to 9 Rickettsia spp. in 26 hunters, Germany, 2006*
Hunter no. | IgG/IgM |
||||||||
---|---|---|---|---|---|---|---|---|---|
R. conorii | R. slovaca | R. helvetica | R. massiliae | R. mongolitimonae | R. israelensis | R. aeschlimannii | R. felis | R. typhi | |
106 | 0/64 | ||||||||
109 | 64/128 | 64/128 | 64/128 | 64/128 | 64/128 | 32/32 | 64/0 | 0/128 | |
111 | 0/32 | 0/64 | 0/32 | ||||||
113 | 0/128 | 0/64 | |||||||
115 | 0/32 | 0/128 | 0/32 | 0/32 | 0/32 | 0/64 | 0/32 | 0/64 | |
117 | 0/32 | 0/32 | 0/32 | 0/32 | |||||
124 | 0/32 | 0/64 | 0/32 | 0/32 | 0/32 | 0/32 | 0/64 | ||
127 | 0/128 | 0/64 | |||||||
130 | 0/64 | 0/64 | 0/128 | 0/32 | 0/32 | 0/64 | 0/64 | ||
131 | 256/0 | 0/64 | |||||||
142 | 0/64 | 0/64 | 0/64 | 0/64 | 0/64 | ||||
148 | 0/64 | 0/64 | 0/64 | 0/32 | |||||
151 | 0/64 | 0/64 | 0/64 | 0/64 | 0/64 | ||||
160 | 0/32 | 0/32 | 0/32 | 0/32 | |||||
161 | 0/64 | 0/64 | 0/32 | 0/32 | |||||
182 | 128/0 | ||||||||
185 | 64/64 | ||||||||
224 | 64/64 | 64/64 | 64/64 | 64/64 | 64/64 | 64/64 | 64/64 | 64/64 | 64/64 |
230 | 0/32 | 0/32 | 0/32 | ||||||
233 | 0/32 | 0/32 | 0/32 | 0/32 | 0/32 | 64/16 | |||
236 | 64/16 | ||||||||
237 | 64/32 | ||||||||
277 | 64/32 | 64/32 | |||||||
281 | 64/32 | ||||||||
285 | 0/32 | 0/32 | 0/32 | 0/32 | 0/32 | ||||
297 | 0/32 | 0/32 | 0/32 | 0/32 | 0/32 | 0/32 | 0/32 | 0/32 |
*All specimens were tested for all antigens. Boldface indicates nonspecific titers. Cutoff titers for seropositivity (immunoglobulin [Ig] G or IgM) were 128/64 for R. conorii and 64/32 for other antigens (8). A rickettsial antigen was considered to represent the agent of infection when cross-reactions were absent or when titers of IgG or IgM antibody against this antigen were >2 serial dilutions higher than titers of IgG or IgM antibody against other rickettsial antigens.
References
- Parola P, Paddock CD, Raoult D. Tick-borne rickettsioses around the world: emerging diseases challenging old concepts. Clin Microbiol Rev. 2005;18:719–56. DOIPubMedGoogle Scholar
- Burgdorfer W, Aeschlimann A, Peter O, Hayes SF, Philip RN. Ixodes ricinus: vector of a hitherto undescribed spotted fever group agent in Switzerland. Acta Trop. 1979;36:357–67.PubMedGoogle Scholar
- Beati L, Péter O, Burgdorfer W, Aeschlimann A, Raoult D. Confirmation that Rickettsia helvetica sp. nov. is a distinct species of the spotted fever group of rickettsiae. Int J Syst Bacteriol. 1993;43:521–6.PubMedGoogle Scholar
- Fournier PE, Allombert C, Supputamongkol Y, Caruso G, Brouqui P, Raoult D. Aneruptive fever associated with antibodies to Rickettsia helvetica in Europe and Thailand. J Clin Microbiol. 2004;42:816–8. DOIPubMedGoogle Scholar
- Nilsson K, Lindquist O, Påhlson C. Association of Rickettsia helvetica with chronic perimyocarditis in sudden cardiac death. Lancet. 1999;354:1169–73. DOIPubMedGoogle Scholar
- Hartelt K, Oehme R, Frank H, Brockmann S, Hassler D, Kimmig P. Pathogens and symbionts in ticks: prevalence of Anaplasma phagocytophilum (Ehrlichia sp.), Wolbachia sp., Rickettsia sp., and Babesia sp. in southern Germany. Int J Med Microbiol. 2004;293:86–92.PubMedGoogle Scholar
- La Scola B, Raoult D. Laboratory diagnosis of rickettsioses: current approaches to diagnosis of old and new rickettsial diseases. J Clin Microbiol. 1997;35:2715–27.PubMedGoogle Scholar
- Simser JA, Palmer AT, Fingerle V, Wilske B, Kurtti TJ, Munderloh UG. Rickettsia monacensis sp. nov., a spotted fever group Rickettsia, from ticks (Ixodes ricinus) collected in a European city park. Appl Environ Microbiol. 2002;68:4559–66. DOIPubMedGoogle Scholar
- Fingerle V, Goodman JL, Johnson RC, Kurtti TJ, Munderloh UG, Wilske B. Human granulocytic ehrlichiosis in southern Germany: increased seroprevalence in high-risk groups. J Clin Microbiol. 1997;35:3244–7.PubMedGoogle Scholar