Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 14, Number 12—December 2008
Dispatch

Novel Borna Virus in Psittacine Birds with Proventricular Dilatation Disease

Kirsi S. Honkavuori, H.L. Shivaprasad, Brent L. Williams, Phenix-Lan Quan, Mady Hornig, Craig Street, Gustavo Palacios, Stephen K. Hutchison, Monique Franca, Michael Egholm, Thomas BrieseComments to Author , and W. Ian Lipkin
Author affiliations: Columbia University, New York, NY, USA (K.S. Honkavuori, B.L. Williams, P.-L. Quan, M. Hornig, C. Street, G. Palacios, T. Briese, W.I. Lipkin); University of California Animal Health and Food Safety Laboratory System–Fresno Branch, Davis, California, USA (H.L. Shivaprasad, M. Franca); 454 Life Sciences, Branford, Connecticut, USA (S.K. Hutchison, M. Egholm)

Main Article

Figure 2

A) Similarity plot between Borna disease virus (BDV) prototype strain V nucleotide sequence and those of characterized BDV strains He/80fr and No/98 compared with novel strains 1367 and 1034/1322. Gene regions corresponding to the nucleoprotein (N), phosphoprotein (P), X protein (X), matrix protein (M), glycoprotein (G) and L-polymerase protein (L), and nucleotide positions are indicated. B) A tree representing the evolutionary history was inferred by using the neighbor-joining method. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (500 replicates) is shown next to the branches. The tree is drawn to scale with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree (number of base substitutions per site; see scale bar). Evolutionary distances were computed by using a Kimura 2-parameter model; a total of 5,449 positions in the final dataset were analyzed by using MEGA4 software (www.megasoftware.net).

Figure 2. A) Similarity plot between Borna disease virus (BDV) prototype strain V nucleotide sequence and those of characterized BDV strains He/80fr and No/98 compared with novel strains 1367 and 1034/1322. Gene regions corresponding to the nucleoprotein (N), phosphoprotein (P), X protein (X), matrix protein (M), glycoprotein (G) and L-polymerase protein (L), and nucleotide positions are indicated. B) A tree representing the evolutionary history was inferred by using the neighbor-joining method. The percentage of replicate trees in which the associated taxa clustered together in the bootstrap test (500 replicates) is shown next to the branches. The tree is drawn to scale with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree (number of base substitutions per site; see scale bar). Evolutionary distances were computed by using a Kimura 2-parameter model; a total of 5,449 positions in the final dataset were analyzed by using MEGA4 software (www.megasoftware.net).

Main Article

Page created: July 22, 2010
Page updated: July 22, 2010
Page reviewed: July 22, 2010
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external