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Volume 14, Number 3—March 2008


Hemagglutinating Encephalomyelitis Coronavirus Infection in Pigs, Argentina

Maria A. Quiroga*Comments to Author , Javier Cappuccio*, Pablo E. Piñeyro*, Walter Basso*, Gastón Moré*, Mariana Kienast†, Sergio Schonfeld‡, José L. Cáncer‡, Sandra Arauz*, María E. Pintos*, Mariana Nanni†, Mariana Machuca*, Norio Hirano§, and Carlos J. Perfumo*
Author affiliations: *Universidad Nacional de la Plata, La Plata, Argentina; †Centro de Investigaciones en Ciencias Veterinarias, Castelar, Argentina; ‡Private practice, Roque Perez, Argentina; §Iwate University, Morioka, Japan;

Main Article


Clinical signs and results of histopathologic examination, IHC testing, and RT-PCR from piglets affected by PHE-CoV*

Organ Days old (days with clinical signs) IHC RT-PCR Histopathologic diagnosis
Brain stem 6 (2) + + Encephalitis
Brain stem 8 (4) + + Encephalitis
Trigeminal ganglion 8 (4) + + Focal ganglioneuritis
Brain stem 8 (4) ND ND Encephalitis
Spinal cord 9 (5) ND + Myelitis
Tonsil 9 (5) ND ND Necrotizing tonsilitis
Brain stem 9 (5) ND ND Meningoencephalitis
Medulla oblongata 11(6) + + Meningoencephalitis

*IHC, immunohistochemical; RT-PCR, reverse transcription–PCR; PHE-CoV, porcine hemagluttinating encephalomyelitis coronavirus; ND, not done; +, positive.

Main Article