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Volume 15, Number 8—August 2009

Extreme Drug Resistance in Acinetobacter baumannii Infections in Intensive Care Units, South Korea

Young Kyoung Park1, Keun Hwa Lee1, Hae Suk Cheong, Doo-Ryeon Chung, Jae-Hoon Song, and Kwan Soo KoComments to Author 
Author affiliations: Sungkyunkwan University School of Medicine, Suwon, South Korea (Y.K. Park, K.R. Peck, H.S. Cheong, D.-R. Chung, J.-H. Song, K.S. Ko); Asian-Pacific Research Foundation for Infectious Diseases, Seoul, South Korea (J.-H. Song, K.S. Ko); 1These authors contributed equally to this article.

Main Article


Clinical characteristics of 8 patients infected with extremely drug-resistant Acinetobacter baumannii isolates, South Korea*

Strain no. Patient age/sex Underlying disease Infection† Days before isolation
bacteremia 30-d outcome Infection-related death
Hospitalized In ICU
07AC–052 60 y/F Acute myeloid leukemia Pneumonia 15 8 No Died Yes
07AC–159 79 y/M Lymphoma Pneumonia 35 9 No Died No
07AC–192 50 y/M Status postliver transplantation Pneumonia 256 2 Yes Survived NA
07AC–204 55 y/F Steven-Johnson syndrome Pneumonia 13 13 Yes Survived NA
07AC–336 16 mo/M Medulloblastoma Pneumonia 32 13 Yes Died Yes
07AC–347 17 mo/M Hepatoblastoma Pneumonia 135 28 No Died Yes
07AC–329 1 mo/F Edward syndrome Colonization‡ 33 33 NA NA NA
07AC–063 56 y/M Lung cancer Colonization‡ 26 21 NA NA NA

*ICU, intensive care unit; NA, not applicable. All but 1 patient (with strain 07AC–192) had mechanical ventilators. Four patients (with strains 07AC–159, 07AC–192, 07AC–336, and 07AC–063) were immunocompromised hosts who had daily administration of corticosteroid (>20 mg/d of prednisolone or an equivalent drug) during >2 wk and treatment with chemotherapy for an underlying malignancy during 1 month before hospital admission.
†Infection is defined as invasion of the body tissues by microorganisms resulting in disease.
‡Colonization occurs when an agent’s presence in a host does not cause a specific immune response or infection.

Main Article

Page created: October 14, 2010
Page updated: October 14, 2010
Page reviewed: October 14, 2010
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