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Volume 15, Number 8—August 2009


Chronic Invasive Aspergillosis caused by Aspergillus viridinutans

Donald C. Vinh1, Yvonne R. Shea1, Pamela A. Jones, Alexandra F. Freeman, Adrian Zelazny, and Steven M. HollandComments to Author 
Author affiliations: National Institutes of Health, Bethesda, Maryland, USA (D.C. Vinh, Y.R. Shea, P.A. Jones, A. Zelazny, S.M. Holland); National Cancer Institute-Frederick, Frederick, Maryland, USA (A.F. Freeman)

Main Article


Antifungal drug susceptibility results of Aspergillus viridinutans isolates relative to A. fumigatus reported at 48 hours*

Isolate Amphotericin B MIC, mg/L Itraconazole MIC, mg/L Voriconazole MIC, mg/L Posaconazole MIC, mg/L Caspofungin MEC, mg/L Terbinafine MIC, mg/L
Patient 1 4 1 1 0.06 0.25 ND
Patient 2† 2–8 8 2–4 <0.016–0.5 0.06–0.25 0.125–1
A. fumigatus B-5233‡ 0.5 0.5 0.5 0.125 0.25 2

*MEC, minimal effective concentration; ND, not determined.
†Composite results of 3 isolates from the patient.
‡Clinical isolate from patient with a fatal case of aspergillosis (courtesy of K.J. Kwon-Chung, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA).

Main Article

1These authors contributed equally to this article.