Pandemic (H1N1) 2009 Outbreak on Pig Farm, Argentina
Ariel Pereda
1 , Javier Cappuccio
1, María A. Quiroga, Elsa Baumeister, Lucas Insarralde, Mariela Ibar, Ramón Sanguinetti, Maria L. Cannilla, Débora Franzese, Oscar E. Escobar Cabrera, Maria I. Craig, Agustina Rimondi, Mariana Machuca, Rosa T. Debenedetti, Carlos Zenobi, Leonardo Barral, Rodrigo Balzano, Santiago Capalbo, Adriana Risso, and Carlos J. Perfumo
Author affiliations: Instituto Nacional de Tecnología Agropecuaria, Castelar, Buenos Aires, Argentina (A. Pereda, M.I. Craig, A. Rimondi); Universidad Nacional de La Plata, La Plata, Buenos Aires (J. Cappuccio, M.A. Quiroga, L. Insarralde, M. Ibar, M. Machuca, C.J. Perfumo); Instituto Nacional de Enfermedades Infecciosas–Administración Nacional de Laboratorios e Institutos de Salud, Buenos Aires (E. Baumeister); Servicio Nacional de Sanidad Animal, Martínez, Buenos Aires (R. Sanguinetti, M.L. Cannilla, D. Franzese, O.E. Escobar Cabrera, R.T. Debenedetti, C. Zenobi, L. Barral, R. Balzano); private veterinary practice, Buenos Aires (S. Capalbo, A. Risso)
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Figure
Figure. Postmortem samples from clinically affected pigs, Argentina, 2009. A) Macroscopic lung lesions with distinctive scattered dark-red foci of lobular consolidation (chessboard-like) in all lobes. B) Severe necrotizing bronchiolitis with partially denuded epithelia. Hematoxylin-eosin stain; original magnification ×400. C) General view of the alveolar walls showing moderate interstitial thickening by leukocytes. Hematoxin-eosin stain; original magnification ×200. D) Bronchioli. Positive-labeled nuclei and cytoplasm of bronchial epithelial cells and mononuclear cells in the alveoli. 3,3′-diaminobenzidine counterstain with hematoxylin stain; original magnification ×200.
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