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Volume 17, Number 12—December 2011


Candidate Cell Substrates, Vaccine Production, and Transmissible Spongiform Encephalopathies

Pedro PiccardoComments to Author , Larisa Cervenakova, Irina Vasilyeva, Oksana Yakovleva, Igor Bacik, Juraj Cervenak, Carroll McKenzie, Lubica Kurillova, Luisa Gregori, Kitty Pomeroy, and David M. Asher
Author affiliations: University of Edinburgh, Easter Bush, UK, (P. Piccardo); Food and Drug Administration, Kensington, Maryland, USA (P. Piccardo, I. Bacik, J. Cervenak, L. Kurillova, L. Gregori, K. Pomeroy, D.M. Asher); Holland Laboratory American Red Cross, Rockville, Maryland, USA (L. Cervenakova, I. Vasilyeva, O. Yakovleva, C. McKenzie)

Main Article

Table 3

Cell lines exposed to sCJD or normal human brain suspension and bioassayed in TgHu mice*

Vero 19 10 650
CHO 18 9 580
R9ab 18 10 580

*sCJD, sporadic Creutzfeldt-Jakob disease; TgHu, transgenic mice expressing human prion protein gene; NB, normal brain; dpi, days postinoculation at cull; Vero, African green monkey kidney; CHO, Chinese hamster ovary; R9ab, rabbit fibroblasts.

Main Article