Volume 17, Number 2—February 2011
Research
Severe Cases of Pandemic (H1N1) 2009 in Children, Germany
Mathias Altmann
, Lena Fiebig, Jana Soyka, Rüdiger von Kries, Manuel Dehnert, and Walter Haas
, Lena Fiebig, Jana Soyka, Rüdiger von Kries, Manuel Dehnert, and Walter Haas
Table 3
Clinical course for children with severe pandemic (H1N1) 2009, Germany, 2009–2010*
| Characteristic | Total | Nonsurvivors not in PICU | Admitted to PICU |
|||
|---|---|---|---|---|---|---|
| Survivors | Nonsurvivors | Subtotal | p value | |||
| Time course of illness, d | ||||||
| Symptom to hospital admission | 77, 2 (1–5) | 3, 1 (1–2) | 65, 2 (1–5) | 9, 1 (1–3) | 74, 2 (1–5) | 0.700 |
| Hospitalization to PICU admission | 74, 0 (0–1) | NA | 65, 0 (0–1) | 9, 1 (0–3) | 74, 0 (0–1) | 0.236 |
| PICU length of stay | 80, 8 (3–17) | NA | 69, 9 (3–18) | 11, 2 (0–8) | 80, 8 (3–17) | NC |
| Hospital length of stay | 83, 14 (5–23) | 3, 5 (3–12) | 69, 16 (7–25) | 11, 3 (2–12) | 80, 14.5 (5.5–23.5) | NC |
| Symptom onset to outcome† |
85, 16 (8–26) |
4, 5.5 (5–9.5) |
72, 18.5 (10.5–29.5) |
9, 8 (3–12) |
81, 17 (8–27) |
NC |
| Time to treatment, d | ||||||
| Symptom onset to oseltamivir treatment | 45, 4 (1–7) | 1, 4‡ | 39, 4 (1–7) | 5, 4 (2–8) | 44, 4 (1–7) | 0.551 |
*Values given are total no. with available information, median (IQR) ,except as indicated. PICU, pediatric intensive care unit; IQR, interquartile range; NA, not applicable (not admitted to PICU); NC, not compared because of different outcomes (release for survivors and death for nonsurvivors).
†Including patients with hospital-acquired pandemic (H1N1) 2009 infection.
‡Only 1 observation.
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