Volume 17, Number 4—April 2011
Dispatch
Vaccinia Virus Infections in Martial Arts Gym, Maryland, USA, 2008
Table
Characteristics of 4 cases of vaccinia infection at a martial arts gym, Maryland, USA, 2008*
Case-patient no.† |
Age, y/sex |
Date of onset |
Rash features |
Initial diagnosis |
PCR |
Serologic results |
1 | 26/M | Jun 16 | Pustules on face, arm, back of knee | Unknown viral exanthem | + | NA |
2 | 28/M | Mid–late Jun | Vesicles on right forearm | None | Weak + | IgM+ (0.243), IgG+ (0.116) |
3 | 31/M | Jun 25 | Unknown presentation | MRSA‡ | NA | IgM+ (0.389), IgG+ (0.227) |
4 | 31/M | Late Jun/early Jul | Unknown presentation | MRSA‡ | NA | IgM+ (0.137), IgG+ (0.2195) |
*Ig, immunoglobulin; NA, not applicable; MRSA, methicillin-resistant Staphylococcus aureus.
†For purposes of this investigation, a case-patient is defined as a person whose clinical samples are positive for vaccinia virus DNA by PCR, or a person with lesions or a rash (macular, papular, vesicular, or pustular) and whose serum sample was positive for anti-orthopoxvirus IgM antibodies (indicative of a recent orthopoxvirus exposure). No case-patients had received a previous smallpox vaccination.
‡Clinically diagnosed, no laboratory confirmation.
1These authors contributed equally to this article.