Volume 17, Number 4—April 2011
CME ACTIVITY - Research
Mumps Complications and Effects of Mumps Vaccination, England and Wales, 2002–2006
Chee-Fu Yung
, Nick Andrews, Antoaneta Bukasa, Kevin E. Brown, and Mary Ramsay
, Nick Andrews, Antoaneta Bukasa, Kevin E. Brown, and Mary Ramsay
Table 2
Association between receipt of vaccination and mumps complications, adjusted for age and sex, England and Wales, April 1, 2002–March 31, 2006*
| Complication |
Vaccine dose |
No. cases/total cases (%) |
Unadjusted OR (95% CI) |
Adjusted OR (95% CI) |
| Hospitalization | 0 | 317/8,298 (3.8) | 1 | 1 |
| 1 | 122/6,312 (1.9) | 0.50 (0.40–0.61) | 0.54 (0.43–0.68) | |
| 2 |
13/914 (1.4) |
0.36 (0.21–0.64) |
0.45 (0.25–0.80) |
|
| Orchitis† | 0 | 356/4,574 (7.8) | 1 | 1 |
| 1 | 123/3,241 (3.8) | 0.44 (0.36– 0.55) | 0.72 (0.56–0.93) | |
| 2 |
7/475 (1.5) |
0.17 (0.08–0.37) |
0.64 (0.28–1.44) |
|
| Meningitis | 0 | 42/8,298 (0.5) | 1 | 1 |
| 1 | 10/6,312 (0.2) | 0.31 (0.16–0.62) | 0.28 (0.14–0.56) | |
| 2 |
1/914 (0.1) |
0.22 (0.03–1.57) |
0.17 (0.02–1.26) |
|
| Pancreatitis | 0 | 26/8,298 (0.3) | 1 | 1 |
| 1 | 12/6,312 (0.2) | 0.61 (0.31–1.20) | 0.95 (0.41–2.19) | |
| 2 | 0/914 | 0 (0–1.34)‡ | – |
*OR, odds ratio; CI, confidence interval; –, not estimable.
†Adjusted for age only.
‡Exact CI.
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