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Volume 17, Number 4—April 2011


Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010

Joanne E. EnstoneComments to Author , Puja R. Myles, Peter J.M. Openshaw, Elaine M. Gadd, Wei Shen Lim, Malcolm G. Semple, Robert C. Read, Bruce L. Taylor, James McMenamin, Colin Armstrong, Barbara Bannister, Karl G. Nicholson, and Jonathan S. Nguyen-Van-Tam
Author affiliations: Author affiliations: University of Nottingham, Nottingham, UK (J.E. Enstone, P.R. Myles, J.S. Nguyen-Van-Tam); Imperial College, London, UK (P.J.M. Openshaw); Department of Health, London (E.M. Gadd, C. Armstrong, B. Bannister); Nottingham University Hospitals National Health Service Trust, Nottingham (W.S. Lim); University of Liverpool, Liverpool, UK (M.G. Semple); University of Sheffield, Royal Hallamshire Hospital, Sheffield, UK (R.C. Read); Portsmouth Hospitals National Health Service Trust, Portsmouth, UK (B.L. Taylor); Health Protection Scotland, Glasgow, Scotland (J. McMenamin); University Hospitals of Leicester National Health Service Trust, Leicester, UK (K.G. Nicholson)

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Table 4

Timelines and outcome for 15 hospitalized children with nosocomial pandemic (H1N1) 2009, United Kingdom, 2009–2010

Patient no. Age/sex Duration, d
Maximum level of care* Outcome
Hospital admission to symptom onset Symptom onset to receipt of antiviral therapy
16 12 y/F 10 Not given 3 Recovered
17 2 y/M 24 Not given 0/1 Died at home
18 4 y/F 54 2† 0/1 Recovered
19 15 y/M 11 8 0/1 Recovered
20 123 d/F 123‡ Unknown data 3 Died after transfer to another hospital
21 1 y/F 14 1 0/1 Recovered
22 1 y/M 6 5 3 Recovered
23 9 y/M Unknown (transferred) 3 3 Recovered
24 12 y/M 14 Not given 0/1 Recovered
25 82 d/M 82‡ 1 3 Died§
26 64 d/M 64‡ Not given 1 Recovered
27 151 d/M 151‡ 3 3 Recovered
28 101 d/F 101‡ 1 3 Recovered
29 41 d/F 41‡ 1 3 Recovered
30 9 y/F 12 1 0/1 Recovered

*Level 3 care is given to patients requiring advanced respiratory support alone or basic respiratory support and support for >2 organ systems; this level includes all patients with complex conditions that required support for multiorgan failure (intensive care unit). Level 0 care is given to patients whose care needs can be met through normal ward care. Level 1 care is given to patients at risk for a deteriorating condition or recently relocated from higher levels of care whose needs can be met in an acute-care ward with additional advice and support from the critical-care team.
†Oseltamivir was replaced with zanamivir on day 11 because of identification of the H275Y drug-resistant mutation (patient also received acyclovir throughout hospitalization);
‡Inpatient since birth.
§Attributed to pandemic (H1N1) 2009.

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