Volume 17, Number 7—July 2011
Research
Severe Plasmodium knowlesi Malaria in a Tertiary Care Hospital, Sabah, Malaysia
Timothy William, Jayaram Menon, Giri S. Rajahram, Leslie Chan, Gordon Ma, Samantha Donaldson, Serena Khoo, Charlie Fredrick, Jenarun Jelip, Nicholas M. Anstey, and Tsin Wen Yeo
Table 2
Laboratory results for patients with severe and uncomplicated Plasmodium knowlesi malaria, Sabah, Malaysia, 2007–2009*
| Laboratory result | Uncomplicated disease, n = 34 | Severe disease, n = 22 |
|---|---|---|
| Parasite count† | 3 (1–4) | 4 (2–4) |
| Hemoglobin concentration, gm/dL† | 13.4 (9.1–17.6) | 11.3 (6.2–16.8) |
| Leukocyte count, × 103 cells/µL† | 6.3 (3.4–15.3) | 12.7 (3.5–21.6) |
| Neutrophil count, × 103 cells/µL† | 3.9 (1.4–10.1) | 9.0 (2.73–16.9) |
| Lymphocyte count × 103 cells/µL† | 1.6 (0.6–3.3) | 2.3 (0.24–6.4) |
| Prothrombin time, s† | 13.8 (10.6–17.5)‡ | 14.9 (11.7–21)§ |
| Partial thromboplastin time, s† | 40 (29.9–57.6)‡ | 57 (31–136)§ |
| Platelet count × 103 cells/µL† | 72 (21–227) | 40 (12–130) |
| Serum creatinine, µmol/L† | 92.6 (57–168) | 289 (53–819) |
| Serum sodium concentration, mmol/L† | 136 (128–146) | 131 (123–140) |
| Serum total bilirubin, µmol/L | 25.2 (4–48)¶ | 173 (11–660) |
| Serum albumin, gm/dL† | 38 (26–73)# | 22 (18–27) |
*All values are mean (range).
†p<0.05 by Student t test or Mann Whitney U test.
‡n = 23.
§n = 19.
¶n = 15.
#n = 13.
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