Novel Human Reovirus Isolated from Children with Acute Necrotizing Encephalopathy
Louise A. Ouattara, Francis Barin, Marie Anne Barthez, Bertrand Bonnaud, Philippe Roingeard, Alain Goudeau, Pierre Castelnau, Guy Vernet, Gláucia Paranhos-Baccalà
, and Florence Komurian-Pradel
Author affiliations: Author affiliations: Fondation Mérieux, Lyon, France (L.A. Ouattara, G. Vernet, G. Paranhos-Baccalà, F. Komurian-Pradel); Centre Hospitalier Universitaire Bretonneau (F. Barin, P. Roingeard, A. Goudeau); Institut National de la Santé et de la Recherche Médicale U966, Tours, France (F. Barin, P. Roingeard, A. Goudeau); Centre Hospitalier Universitaire, Clocheville, Tours (M.A. Barthez, P. Castelnau); bioMérieux SA, Marcy l’Etoile, France (B. Bonnaud)
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Figure 2
Figure 2. Electron microscopic images of the cytopathic effect induced in MRC5 cells by a reovirus isolate from throat specimens of patient 2, a 22-month-old girl with acute necrotizing ancephalopathy. N, nucleus; arrows indicate viral intracytoplasmic inclusions. Scale bars indicate 2 µm (A) or 0.2 µm (B).
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