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Volume 17, Number 8—August 2011
Dispatch

Human Parvovirus 4 as Potential Cause of Encephalitis in Children, India

Laura A. Benjamin, Penny Lewthwaite, Ravi Vasanthapuram, Guoyan Zhao, Colin P. Sharp, Peter Simmonds, David Wang, and Tom SolomonComments to Author 
Author affiliations: Author affiliations: University of Liverpool Institute of Infection and Global Health, Liverpool, UK (L.A. Benjamin, P. Lewthwaite, T. Solomon); Walton Centre National Health Service Foundation Trust, Liverpool (L.A. Benjamin, T. Solomon); Vijayanagar Institute of Medical Sciences, Bellary, India (R. Vasanthapuram); Washington University, St. Louis, Missouri, USA (G. Zhao, D. Wang); University of Edinburgh, Edinburgh, Scotland (C. Sharp, P. Simmonds)

Main Article

Table 1

Clinical and laboratory characteristics of children with CSF positive for human parvovirus 4, India*

ID, date of illness
 Age, y
 Clinical course
 Outcome
 CSF
Serum
PCR
 WCC†
 Protein, mg/dL
 Glucose, mg/dL
 IgM
 IgG
 PCR
VES085,
2006 Jan
 2
 Prodomal illness for 12 days; febrile with frequent generalized convulsions during first week of admission; CSF examination on day 12 of illness
 Discharged against medical advice on day 18 after admission
 +
1.5 x 107 copies/mL
 4
 59
 32
+
 −
 +
5.6 x 109 copies/mL
VES065
2005 Nov 3 Prodomal illness for 9 days; febrile, poor appetite, and a generalized convulsion on day 9; CSF examination on day 9 of illness Recovered on day 14 with no residual neurologic deficit +
3.2 x 105 copies/mL 8 15 60 NA NA NA

*CSF, cerebrospinal fluid; ID, patient identification code; WCC, leukocyte count; Ig, immunoglobulin; +, positive; −, negative; NA, not available.
†Leukocyte count differential 100% lymphocytes for each patient.

Main Article

Page created: August 15, 2011
Page updated: August 15, 2011
Page reviewed: August 15, 2011
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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