Volume 18, Number 1—January 2012
Dispatch
Emergence of Blastoschizomyces capitatus Yeast Infections, Central Europe
Table 2
Patient no. | MIC, μg/mL |
||||||
---|---|---|---|---|---|---|---|
AMB | 5-FC | FLC | ITC | VRC | POS | CAS | |
1 | 0.5 | 0.03 | 2 | 0.06 | 0.016 | 0.25 | 4 |
2 | 0.5 | 0.03 | 8 | 0.12 | 0.06 | 0.25 | 4 |
3 | 0.5 (3)† | 0.06 | 4 | 0.06 | 0.06 | 0.25 | 8 |
4 | 0.5 | 16 | 1 | 0.032 | 0.032 | 0.064 | 4 |
5 | 0.5 | 0.12 | 16 | 0.25 | 0.25 | 0.5 | >16 |
*AMB, deoxycholate amphotericin B; 5-FC, 5-fluorocytosine; FLC, fluconazole; ITC, itraconazole; VRC, voriconazole; POS, posaconazole; CAS, caspofungin.
†By Etest (bioMérieux, Marcy l’Etoile, France), the isolate had an AMB MIC of 3 μg/mL.
References
- Malani AN, Kauffman CA. Changing epidemiology of rare mould infections: implications for therapy. Drugs. 2007;67:1803–12. DOIPubMedGoogle Scholar
- Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin Infect Dis. 2005;41:634–53. DOIPubMedGoogle Scholar
- Imhof A, Balajee SA, Fredricks DN, Englund JA, Marr KA. Breakthrough fungal infections in stem cell transplant recipients receiving voriconazole. Clin Infect Dis. 2004;39:743–6. DOIPubMedGoogle Scholar
- Casadevall A. Fungal virulence, vertebrate endothermy, and dinosaur extinction: is there a connection? Fungal Genet Biol. 2005;42:98–106. DOIPubMedGoogle Scholar
- Robert VA, Casadevall A. Vertebrate endothermy restricts most fungi as potential pathogens. J Infect Dis. 2009;200:1623–6. DOIPubMedGoogle Scholar
- Bouza E, Munoz P. Invasive infections caused by Blastoschizomyces capitatus and Scedosporium spp. Clin Microbiol Infect. 2004;10(Suppl 1):76–85. DOIPubMedGoogle Scholar
- Girmenia C, Pagano L, Martino B, D'Antonio D, Fanci R, Specchia G, Invasive infections caused by Trichosporon species and Geotrichum capitatum in patients with hematological malignancies: a retrospective multicenter study from Italy and review of the literature. J Clin Microbiol. 2005;43:1818–28. DOIPubMedGoogle Scholar
- Martino R, Salavert M, Parody R, Tomas JF, de la Camara R, Vazquez L, Blastoschizomyces capitatus infection in patients with leukemia: report of 26 cases. Clin Infect Dis. 2004;38:335–41. DOIPubMedGoogle Scholar
- Martino P, Venditti M, Micozzi A, Morace G, Polonelli L, Mantovani MP, Blastoschizomyces capitatus: an emerging cause of invasive fungal disease in leukemia patients. Rev Infect Dis. 1990;12:570–82. DOIPubMedGoogle Scholar
- Pfaller MA, Diekema DJ, Gibbs DL, Newell VA, Meis JF, Gould IM, Results from the ARTEMIS DISK Global Antifungal Surveillance study, 1997 to 2005: an 8.5-year analysis of susceptibilities of Candida species and other yeast species to fluconazole and voriconazole determined by CLSI standardized disk diffusion testing. J Clin Microbiol. 2007;45:1735–45. DOIPubMedGoogle Scholar
- Pfaller MA, Diekema DJ, Merz WG. Infections caused by non-Candida, non-cryptococcal yeasts. In: Anaissie EJ, McGinnis MR, Pfaller MA, editors. Clinical Mycology. 2nd ed. New York: Churchill Livingstone Elsevier; 2009. p. 261.
- Oelz O, Schaffner A, Frick P, Schaer G. Trichosporon capitatum: thrush-like oral infection, local invasion, fungaemia and metastatic abscess formation in a leukaemic patient. J Infect. 1983;6:183–5. DOIPubMedGoogle Scholar
- Freydiere AM, Guinet R, Boiron P. Yeast identification in the clinical microbiology laboratory: phenotypical methods. Med Mycol. 2001;39:9–33.PubMedGoogle Scholar
- Bundesamt für Meteorologie und Klimatologie. Klimatrends Schweiz [cited 2011 Jul 7]. http://www.meteoswiss.admin.ch/web/de/klima/klima_heute/trends_schweiz.html
- Garcia-Solache MA, Casadevall A. Global warming will bring new fungal diseases for mammals. MBio. 2010;1; pii:e00061–10.
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