Volume 18, Number 5—May 2012
Research
Temporal Trends in Bordetella pertussis Populations, Denmark, 1949–2010
Randi Føns Petersen
, Tine Dalby, Ditte Marie Dragsted, Frits Mooi, and Lotte Lambertsen
, Tine Dalby, Ditte Marie Dragsted, Frits Mooi, and Lotte Lambertsen
Table 2
MLVA typing results for isolates analyzed in a study of temporal trends in Bordetella pertussis populations, Denmark, 1949–2009*
| MT | No. isolates detected (% frequency) |
|||
|---|---|---|---|---|
| Total period, n = 260 isolates, 40 MTs | Period 1, n = 24 isolates, 8 MTs | Period 2, n = 51 isolates, 17 MTs | Period 3, n = 185 isolates, 23 MTs | |
| Major MTs | ||||
| 27 | 122 (47) | ND | 3 (6) | 119 (65) |
| 29 | 49 (20) | 3 (12) | 27 (53) | 19 (10) |
| 36 | 8 (3) | ND | ND | 8 (4) |
| 253† | 7 (3) | 7 (29) | ND | ND |
| 34 | 6 (2) | ND | 2 (4) | 4 (2) |
| 141 | 5 (2) | 4 (17) | 1 (2) | ND |
| 18 | 4 (1) | ND | ND | 4 (2) |
| 256† | 4 (1) | 4 (17) | ND | ND |
| 16 | 4 (1) | ND | 1 (2) | 3 (2) |
| Minor MTs‡ | 51 (20) | 6 (25) | 17 (33) | 28 (15) |
*Genetic diversity was calculated as Simpson index of diversity for each period. The genetic diversity index was calculated for MLVA types by using the online tool Comparing Partitions (www.comparingpartitions.info). Simpson index of diversity (95% CI) was 0.74 (0.69–0.79) for the total period, 0.84 (0.75–0.92) for period 1, 0.71 (0.57–0.85) for period 2, and 0.57 (0.48–0.65) for period 3. MLVA, multilocus variable-number tandem repeat analysis; MT, MLVA type; ND, none detected.
†MTs found in 1–3 isolates.
‡New MTs detected in this study.
Page created: April 12, 2012
Page updated: April 12, 2012
Page reviewed: April 12, 2012
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
Content Credential