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Volume 18, Number 5—May 2012


High Anti–Phenolic Glycolipid-I IgM Titers and Hidden Leprosy Cases, Amazon Region

Claudio Guedes SalgadoComments to Author , Denis Vieira Gomes Ferreira, Marco Andrey Cipriani Frade, Layana de Souza Guimarães, Moisés Batista da Silva, and Josafá Gonçalves Barreto
Author affiliations: Federal University of Pará, Marituba, Brazil (C.G. Salgado, D.V.G. Ferreira, L.S. Guimarães, M.B. Silva, J.G. Barreto); Federal University of Pará, Belém, Brazil (C.G. Salgado, M.B. Silva); São Paulo University–Faculty of Medicine, São Paulo, Brazil (M.A.C. Frade); Dr Marcello Candia Reference Unit in Sanitary Dermatology of the State of Pará, Marituba (L.S. Guimarães); Federal University of Pará, Castanhal, Brazil (J.G. Barreto)

Main Article


New leprosy cases detected among selected households, Oriximiná, Pará State, Brazilian Amazon, 2010

Group Household contact anti–PGL-I IgM ELISA result No. households visited No. persons examined No. new cases
Among persons previously tested Among contacts of persons previously tested Total†
Leprosy patients Positive 14 43 9 4 13
Negative 11 42 1 1 2
Students Positive 11 84 5 5 10
Negative 8 53 1 4 5
Total 44 222 16 14 30

*Households were selected from among 35 leprosy patients encountered during the first visit (25 households, 14 with an anti–PGL-I–positive contact in the household and 11 without) and among students with results of anti–PGL-I serology (19 households, 11 with an anti–PGL-I–positive contact in the household and 8 without). PGL-I, phenolic glycolipid-I.
†Fisher exact test comparing case-patients and non–case-patients among those positive or negative for anti-PGL-I IgM revealed a statistically significant difference (p = 0.0280).

Main Article