Volume 18, Number 5—May 2012
Letter
High Anti–Phenolic Glycolipid-I IgM Titers and Hidden Leprosy Cases, Amazon Region
Table
New leprosy cases detected among selected households, Oriximiná, Pará State, Brazilian Amazon, 2010
Group | Household contact anti–PGL-I IgM ELISA result | No. households visited | No. persons examined | No. new cases |
||
---|---|---|---|---|---|---|
Among persons previously tested | Among contacts of persons previously tested | Total† | ||||
Leprosy patients | Positive | 14 | 43 | 9 | 4 | 13 |
Negative | 11 | 42 | 1 | 1 | 2 | |
Students | Positive | 11 | 84 | 5 | 5 | 10 |
Negative | 8 | 53 | 1 | 4 | 5 | |
Total | 44 | 222 | 16 | 14 | 30 |
*Households were selected from among 35 leprosy patients encountered during the first visit (25 households, 14 with an anti–PGL-I–positive contact in the household and 11 without) and among students with results of anti–PGL-I serology (19 households, 11 with an anti–PGL-I–positive contact in the household and 8 without). PGL-I, phenolic glycolipid-I.
†Fisher exact test comparing case-patients and non–case-patients among those positive or negative for anti-PGL-I IgM revealed a statistically significant difference (p = 0.0280).