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Volume 19, Number 5—May 2013

Dispatch

Tick-borne Encephalitis Associated with Consumption of Raw Goat Milk, Slovenia, 2012

Neda Hudopisk, Miša Korva, Evgen Janet, Marjana Simetinger, Marta Grgič-Vitek, Jakob Gubenšek, Vladimir Natek, Alenka Kraigher, Franc Strle, and Tatjana Avšič-ŽupancComments to Author 
Author affiliations: Regional Public Health Institute, Ravne na Koroškem, Slovenia (N. Hudopisk, E. Janet, M. Simetinger); Institute of Microbiology and Immunology, Ljubljana, Slovenia (M. Korva, T. Avšič-Županc); National Institute of Public Health, Ljubljana, Slovenia (M. Grgič-Vitek, A. Kraigher); University Medical Centre Ljubljana, Ljubljana (J. Gubenšek, F. Strle); Regional Hospital Slovenj Gradec, Slovenj Gradec, Slovenia (V. Natek)

Main Article

Table

Epidemiologic characteristics of persons in whom tick-borne encephalitis developed after drinking raw goat milk. Slovenia, 2012*

Patient no., age, y/sex
 Date(s) milk consumed
 Illness phase Date(s) serum sample obtained
First
Second
 Virologic testing
Onset date; clinical signs; duration
 Onset date; clinical signs; duration
 TBEV ELISA
 TBEV NT
 TBEV rRT-PCR
IgM
IgG
1, 31/M
 Apr 18
 Apr 20; fever (38.0°C), chills, headache, vomiting, muscle aches, sore throat, sensitivity to light; nearly 1 wk
May 5; fever (39.8°C), headache, nausea, vomiting, photophobia, poor concentration, blurred vision, tremor; improvement after 8 d
 May 8
 Pos
Pos
 Pos
 Neg
2, 59/F
 Apr 18
 Apr 20; fever (<38.6°C), chills, malaise, loose stools; 5 d
May 3; fever (38.5°C) for 6 d, headache, nausea, confusion, visual disturbances, tremor; marked improvement after 12 d
 May 8
 Pos
Pos
 Pos
 Neg
3, 32/M Apr 17, 18, 20 Apr 20; fever (39.5°C); chills, fatigue, muscle pain; 4 d Not ill May 15 Pos Pos Pos Neg
Jun 6
 Pos
Pos
 Pos
 ND
4, 28/M Apr 18 Not ill Not ill May 15 Neg Pos Pos Neg
Jun 6 Neg Pos Pos ND

*Except for patient 4, no patients were vaccinated against tick-borne encephalitis. For patients 1 and 2, the incubation period was 2 d; for patient 3, the incubation period was 2–3 d. Patient 1 refused hospitalization and was treated as an outpatient; patient 2 was hospitalized for 8 d; patient 3 did not seek medical care. TBEV, tick-borne encephalitis virus; NT, neutralization test; rRT-PCR, real-time reverse transcription PCR; Pos, positive; Neg, negative; ND, not done.

Main Article

Page created: April 01, 2013
Page updated: April 01, 2013
Page reviewed: April 01, 2013
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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