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Volume 19, Number 6—June 2013
Research

Novel Mycobacterium tuberculosis Complex Isolate from a Wild Chimpanzee

Mireia Coscolla, Astrid Lewin, Sonja Metzger, Kerstin Maetz-Rennsing, Sébastien Calvignac-Spencer, Andreas Nitsche, Pjotr Wojtek Dabrowski, Aleksandar Radonic, Stefan Niemann, Julian Parkhill, Emmanuel Couacy-Hymann, Julia Feldman, Iñaki Comas, Christophe Boesch, Sebastien Gagneux1, and Fabian H. Leendertz1Comments to Author 
Author affiliations: Swiss Tropical and Public Health Institute, Basel, Switzerland (M. Coscolla, J. Feldman, S. Gagneux); University of Basel, Basel (M. Coscolla, J. Feldman, S. Gagneux); Centro Superior de Investigación en Salud Pública, Valencia, Spain (M. Coscolla, I. Comas); Robert Koch-Institut, Berlin, Germany (A. Lewin, S. Metzger, S. Calvignac-Spencer, A. Nitsche, P. Wojtek Dabrowski, A. Radonic, F.H. Leendertz); Max-Planck-Institute for Evolutionary Anthropology, Leipzig, Germany (S. Metzger, C. Boesch); German Primate Center, Goettingen, Germany (K. Maetz-Rennsing); Research Centre Borstel, Borstel, Germany (S. Niemann); Wellcome Trust Sanger Institute, Cambridge, UK (J. Parkhill); Laboratoire Nationale de la Pathologie Animale, Bingerville, Côte d’Ivoire (E. Couacy-Hymann); CIBER in Epidemiology and Public Health, Barcelona, Spain (I. Comas)

Main Article

Figure 2

Histopathologic examination of tissue samples from adult female chimpanzee that was found dead in Taï National Park, Côte d’Ivoire, on August 5, 2009. A) Hematoxylin and eosin (H&E) stain of the spleen shows focal granulomatous inflammation with central accumulation of multinucleated Langhans giant cells (stars) B, C) H&E stain of the liver shows focal granulomatous inflammation within liver parenchyma (B, arrow) and large granulomatous alteration demarcated by fibrous connective tissue

Figure 2. . Histopathologic examination of tissue samples from adult female chimpanzee that was found dead in Taï National Park, Côte d’Ivoire, on August 5, 2009. A) Hematoxylin and eosin (H&E) stain of the spleen shows focal granulomatous inflammation with central accumulation of multinucleated Langhans giant cells (stars). B, C) H&E stain of the liver shows focal granulomatous inflammation within liver parenchyma (B, arrows) and large granulomatous alteration demarcated by fibrous connective tissue infiltrated by Langhans giant cells (C). D) Ziehl-Neelsen stain of the liver shows aggregates of acid-fast bacilli within a large granuloma. Results were consistent with Mycobacterium tuberculosis complex infection.

Main Article

1These authors contributed equally to this article.

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