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Volume 19, Number 9—September 2013

Macrolide-Resistant Mycoplasma pneumoniae in Humans, Ontario, Canada, 2010–2011

AliReza Eshaghi, Nader Memari, Patrick Tang, Romy Olsha, David J. Farrell, Donald E. Low, Jonathan B. Gubbay, and Samir N. PatelComments to Author 
Author affiliations: Ontario Agency for Health Protection and Promotion, Toronto, Ontario, Canada (A. Eshaghi, N. Memari, P. Tang, R. Olsha, D.J. Farrell, D.E. Low, J.B. Gubbay, S.N. Patel); University of Toronto, Toronto (D.J. Farrell, D.E. Low, J.B. Gubbay, S.N. Patel); Mount Sinai Hospital, Toronto (D.E. Low, J.B. Gubbay); The Hospital for Sick Children, Toronto (J.B. Gubbay)

Main Article

Table 2

Typing of Mycoplasma pneumoniae isolates by P1 adhesion gene, Ontario, Canada, 2010–2011*

P1 gene type No. isolates Variant Reference GenBank accession no.† Nucleotide homology, % Amino acid homology, % Nonsynonymous mutations compared with reference (no. isolates) No. VTR AGT sequences No. drug-resistant isolates
1 16 NA M129 U00089.2 99.7–99.9 99.5–99.9 E179K (7), D559N (1), Q1232E (4) 7–11 3
2 8 NA Mp1842 AF290002.1 99.6–99.9 99.5–99.8 S841L, E962D, I1302V 7–11 1
3 2a Mpn309 AP012303.1 99.8–99.9 99.5–99.6 Y210N (1), T837N (3) 6 0
8 2b T-103 AB691539.1 99.5–99.9 99.5–99.9 S1516P: 6 isolates had a deletion at 1244-QTNS-1247 7–9 1
7 2c P033 JN048891.1 99.8–100 99.7–100 V1411E 7–9 0

*VTR, variable tandem repeat. NA, not applicable (strains M129 and Mp1842 are considered prototypes representative for types 1 and 2).
†The sequences of the P1 gene generated in this study have been deposited in GenBank (accession nos. KF154740–KF154759).

Main Article

Page created: August 20, 2013
Page updated: August 20, 2013
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