Volume 19, Number 9—September 2013
Dispatch
Macrolide-Resistant Mycoplasma pneumoniae in Humans, Ontario, Canada, 2010–2011
AliReza Eshaghi, Nader Memari, Patrick Tang, Romy Olsha, David J. Farrell, Donald E. Low, Jonathan B. Gubbay, and Samir N. Patel
Table 2
Typing of Mycoplasma pneumoniae isolates by P1 adhesion gene, Ontario, Canada, 2010–2011*
| P1 gene type | No. isolates | Variant | Reference | GenBank accession no.† | Nucleotide homology, % | Amino acid homology, % | Nonsynonymous mutations compared with reference (no. isolates) | No. VTR AGT sequences | No. drug-resistant isolates |
|---|---|---|---|---|---|---|---|---|---|
| 1 | 16 | NA | M129 | U00089.2 | 99.7–99.9 | 99.5–99.9 | E179K (7), D559N (1), Q1232E (4) | 7–11 | 3 |
| 2 | 8 | NA | Mp1842 | AF290002.1 | 99.6–99.9 | 99.5–99.8 | S841L, E962D, I1302V | 7–11 | 1 |
| 3 | 2a | Mpn309 | AP012303.1 | 99.8–99.9 | 99.5–99.6 | Y210N (1), T837N (3) | 6 | 0 | |
| 8 | 2b | T-103 | AB691539.1 | 99.5–99.9 | 99.5–99.9 | S1516P: 6 isolates had a deletion at 1244-QTNS-1247 | 7–9 | 1 | |
| 7 | 2c | P033 | JN048891.1 | 99.8–100 | 99.7–100 | V1411E | 7–9 | 0 |
*VTR, variable tandem repeat. NA, not applicable (strains M129 and Mp1842 are considered prototypes representative for types 1 and 2).
†The sequences of the P1 gene generated in this study have been deposited in GenBank (accession nos. KF154740–KF154759).
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