Lethal Factor and Anti-Protective Antigen IgG Levels Associated with Inhalation Anthrax, Minnesota, USA
Mark D. Sprenkle
, Jayne Griffith, William Marinelli, Anne E. Boyer, Conrad P. Quinn, Nicki T. Pesik, Alex Hoffmaster, Joseph Keenan, Billie A. Juni, and David D. Blaney
Author affiliations: Hennepin County Medical Center, Minneapolis, Minnesota, USA (M.D. Sprenkle, W. Marinelli); Minnesota Department of Health, St. Paul, Minnesota, USA (J. Griffith, B.A. Juni); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (A.E. Boyer, C.P. Quinn, N.T. Pesik, A. Hoffmaster, D.D. Blaney); University of Minnesota, Minneapolis (J. Keenan)
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Figure 2
Figure 2. . Plasma and pleural fluid lethal factor levels and anti-protective antigen IgG (AIG) levels for a patient from the time of examination in the community hospital emergency department to discharge from the tertiary referral center. Asterisks indicate that anti-protective AIG levels obtained before anthrax immune globulin administration were below the lower limit of quantification. The vertical dashed line represents the time of anthrax immunoglobulin administration. The patient’s initial plasma lethal factor level was 58.0 ng/mL and declined to 1.5 ng/mL before AIG administration. Pleural fluid LF was 16.2 ng/mL at initial drainage and declined steadily.
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Page created: January 17, 2014
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