Skip directly to site content Skip directly to page options Skip directly to A-Z link Skip directly to A-Z link Skip directly to A-Z link
Volume 20, Number 2—February 2014
Research

Lymphocytic Choriomeningitis Virus in Employees and Mice at Multipremises Feeder-Rodent Operation, United States, 2012

Barbara KnustComments to Author , Ute Ströher, Laura Edison, César G. Albariño, Jodi Lovejoy, Emilian Armeanu, Jennifer House, Denise Cory, Clayton Horton, Kathy L. Fowler, Jessica Austin, John Poe, Kraig E. Humbaugh, Lisa Guerrero, Shelley Campbell, Aridth Gibbons, Zachary Reed, Deborah Cannon, Craig Manning, Brett Petersen, Douglas Metcalf, Bret Marsh, Stuart T. Nichol, and Pierre E. Rollin
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA (B. Knust, U. Ströher, L. Edison, C.G. Albarino, L. Guerrero, S. Campbell, A. Gibbons, Z. Reed, D. Cannon, C. Manning, B. Petersen, S.T. Nichol, P.E. Rollin); Georgia Department of Public Health, Atlanta (L. Edison); Indiana Board of Animal Health, Indianapolis, Indiana, USA (J. Lovejoy, D. Metcalf, B. Marsh); Deaconess Hospital, Evansville, Indiana, USA (E. Armeanu); Indiana State Department of Health, Indianapolis (J. House); Vanderburgh County Health Department, Evansville (D. Cory); Green River District Health Department, Owensboro, Kentucky, USA (C. Horton, J. Austin); Kentucky Department for Public Health, Frankfort, Kentucky, USA (K.L. Fowler, J. Poe, K.E. Humbaugh)

Main Article

Table 4

Test results for LCMV from mice and rats in facility A, Indiana, USA, 2012*

Building/room Species No. adult rodents in room Sample size IgG positive
 RT-PCR positive
No. (%) Estimated no. per room (95% CI)† No. (%)‡ Estimated no. per room (95% CI)†
1
1 Rat 1,512 110 0 0 (0–41) 0 0 (0–41)
2
 Rat
 2,058
 83
 0
 0 (0–72)
0
 0 (0–72)
2
1 Mouse 13,104 110 28 (25) 3,342 (2,306–4,534) 4 (4) 472 (131–1,179)
2 Mouse 10,368 110 25 (23) 2,354 (1,586–3,287) 2 (2) 187 (21–664)
3 Mouse 13,104 102 36 (35) 4,626 (3,420–5,949) 0 0 (0–380)
4
 Mouse
 10,368
 110
 42 (38)
 3,961 (3,017–4,966)
1 (1)
 93 (2–508)
3
1 Mouse 14,400 110 3 (3) 389 (86–1,123) 1 (1) 130 (3–706)
2 Mouse 14,400 110 0 0 (0–389) 0 0 (0–389)
3 Mouse 14,400 110 19 (17) 2,491 (1,541–3,701) 0 0 (0–389)
4 Mouse 5,760 109 25 (23) 1,319 (887–1,843) 0 0 (0–156)
5 Mouse 14,400 110 20 (18) 2,621 (1,656–3,845) 0 0 (0–389)
6 Mouse 12,384 110 36 (33) 4,050 (2,984–5,238) 0 0 (0–334)
7
 Mouse
 4,320
 110
 1 (1)
 39 (1–212)
0
 0 (0–117)
4
1 Mouse 11,520 98 37 (38) 4,355 (3,248–5,541) 1 (1) 115 (2–645)
2 Mouse 17,280 108 24 (22) 3,836 (2,557–5,391) 1 (1) 155 (3–881)
3 Rat 5,460 110 0 0 (0–147) 0 0 (0–147)
4 Rat 4,704 110 0 0 (0–127) 0 0 (0–127)

*LCMV, lymphocytic choriomeningitis virus; RT-PCR, reverse transcription PCR.
†Binomial estimators were used to calculate 95% CIs for the entire adult population for each room, based on the number of test-positive animals detected with the samples obtained.
‡All RT-PCR–positive animals were LCMV IgG-negative as measured by ELISA.

Main Article

Page created: January 17, 2014
Page updated: January 17, 2014
Page reviewed: January 17, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
file_external