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Volume 20, Number 2—February 2014
Dispatch

Congenital Rubella Syndrome in Child of Woman without Known Risk Factors, New Jersey, USA

Samantha I. PittsComments to Author , Gregory S. Wallace, Barbara Montana, Elizabeth F. Handschur, Debrah Meislich, Alethia C. Sampson, Suzanne Canuso, Jennifer Horner, Albert E. Barskey, Emily S. Abernathy, and Joseph P. Icenogle
Author affiliations: Johns Hopkins University School of Medicine, Baltimore, Maryland, USA (S.I. Pitts); New Jersey Department of Health, Trenton, New Jersey, USA (S.I. Pitts, B. Montana, E.F. Handschur, S. Canuso); Council of State and Territorial Epidemiologists, Atlanta, Georgia, USA (S.I. Pitts); Centers for Disease Control and Prevention, Atlanta (G.S. Wallace, A.E. Barskey, E.S. Abernathy, J.P. Icenogle); Cooper Medical School of Rowan University, Camden, New Jersey, USA (D. Meislich); Burlington County Health Department, Westampton, New Jersey, USA (A.C. Sampson, J. Horner)

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Table

Criteria of the Council of State and Territorial Epidemiologists (2009) for a confirmed case of congenital rubella*

Criteria Criteria met by case-patient
Clinical criteria
Congenital heart disease† Yes
Microcephaly Yes
Developmental delay Yes
Hepatosplenomegaly Yes
Purpura No
Cataracts/congenital glaucoma No
Hearing impairment No
Pigmentary retinopathy No
Jaundice No
Meningoencephalitis No
Radiolucent bone disease
No
Laboratory criteria
Demonstration of rubella IgM Yes
Persistent rubella antibody in an infant Yes
Positive rubella RT-PCR Yes
Isolation of rubella virus No

*RT-PCR, reverse transcription PCR. Source (4).
†Usually patent ductus arteriosus or peripheral pulmonary artery stenosis.

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References
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  3. Centers for Disease Control and Prevention. Three cases of congenital rubella syndrome in the postelimination era—Maryland, Alabama, and Illinois, 2012. MMWR Morb Mortal Wkly Rep. 2013;62:2269 .PubMedGoogle Scholar
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  8. Bellini  WJ, Icenogle  JP. Measles and rubella viruses. In: Murray PR, Baron EJ, Jorgensen JH, Landry ML, Pfaller MA, editors. Manual of clinical microbiology, 9th ed. Washington (DC): American Society for Microbiology; 2007. p. 1389–403.
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Page created: January 17, 2014
Page updated: January 17, 2014
Page reviewed: January 17, 2014
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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