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Volume 20, Number 6—June 2014
Research

Genetic Evidence of Importation of Drug-Resistant Plasmodium falciparum to Guatemala from the Democratic Republic of the Congo

Jaymin C. PatelComments to Author , Steve M. Taylor, Patricia C. Juliao, Christian M. Parobek, Mark Janko, Luis Demetrio Gonzalez, Lucia Ortiz, Norma Padilla, Antoinette K. Tshefu, Michael Emch, Venkatachalam Udhayakumar, Kim Lindblade, and Steven R. Meshnick
Author affiliations: University of North Carolina, Chapel Hill, North Carolina, USA (J.C. Patel, S.M. Taylor, C.M. Parobek, M. Janko, M. Emch, S.R. Meshnick); Centers for Disease Control and Prevention, Atlanta, Georgia, USA (P.C. Juliao, V. Udhayakumar, K. Lindblade); Military Medical Center, Guatemala City, Guatemala (L.D. Gonzalez); Universidad de Valle de Guatemala, Guatemala City (L. Ortiz, N. Padilla); University of Kinshasa, Kinshasa, Democratic Republic of the Congo (A.K. Tshefu)

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Figure 4

Phylogenetic tree showing predicted clustering between Plasmodium falciparum populations from the Democratic Republic of Congo (DRC), soldiers returning to Guatemala from the DRC, and Guatemala. The predicted split between parasites identified in samples taken in Guatemala and parasites from DRC among soldiers was significant (95% CI >99.9%) (black bar); the predicted split between parasites from DRC and returning soldiers was not significant (95% CI 50%–70%) (white bar). Computed by using Fa

Figure 4. Phylogenetic tree showing predicted clustering between Plasmodium falciparum populations from the Democratic Republic of Congo (DRC), soldiers returning to Guatemala from the DRC, and GuatemalaThe predicted split between parasites identified in samples taken in Guatemala and parasites from DRC among soldiers was significant (95% CI >99.9%) (black bar); the predicted split between parasites from DRC and returning soldiers was not significant (95% CI 50%–70%) (white bar)Computed by using Fast UniFrac (30) with jacknifing and 1,000 permutations.

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