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Volume 20, Number 6—June 2014
Dispatch

Infection with Mansonella perstans Nematodes in Buruli Ulcer Patients, Ghana

Richard O. PhillipsComments to Author , Michael Frimpong, Fred S. Sarfo, Birte Kretschmer, Marcus Beissner, Alexander Debrah, Yaw Ampem-Amoako, Kabiru M. Abass, William Thompson, Mabel Sarpong Duah, Justice Abotsi, Ohene Adjei, Bernhard Fleischer, Gisela Bretzel, Mark Wansbrough-Jones, and Marc Jacobsen
Author affiliations: Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (R.O. Phillips, A. Debrah); Komfo Anokye Teaching Hospital, Kumasi (R.O. Phillips, F.S. Sarfo, Y. Ampem-Amoako, O. Adjei); Kumasi Collaborative Centre for Research, Kumasi (M. Frimpong, M. Sarpong Duah); Bernhard Nocht Institute of Tropical Medicine, Hamburg, Germany (B. Kretschmer, B. Fleischer); University Hospital, Ludwig-Maximilians-University of Munich, Munich, Germany (M. Beissner, G. Bretzel); Agogo Presbyterian Hospital, Agogo, Ghana (K.M. Abass, W. Thompson, J. Abotsi); St. George’s University of London, London, UK (M. Wansbrough-Jones); University Children’s Hospital, Dusseldorf, Germany (M. Jacobsen)

Main Article

Table

Characteristics of patients with active Mycobacterium ulcerans infection, monoinfected or co-infected with Mansonella perstans, and of household contacts, Ghana, August 2010–December 2012*

Characteristic No. (%) persons with M. ulcerans infection
 No. (%) household contacts, n = 30 p value
Co-infected with M. perstans, n = 15 Monoinfected, n = 51 Total, n = 66
Age, y 0.514†
<16 4 (27) 24 (47) 28 (42) 15 (50)
16–59
 11 (73)
 27 (53)
 38 (58)
 15 (50)
Sex 1.000†
M 9 (60) 19 (37) 30 (45) 14 (47)
F
 6 (40)
 32 (63)
 36 (55)
 16 (53)
Clinical form of M. ulcerans infection 0.049‡
Nodule 8 (53) 11 (22) 19 (29) NA
Plaque with edema 2 (12) 17 (33) 19 (29) NA
Ulcer
 5 (35)
 23 (45)
 28 (42)
 NA
Category of M. ulcerans infection 0.910‡
I 9 (59) 32 (63) 41 (62) NA
II 4 (29) 11 (22) 15 (23) NA
III
 2 (12)
 8 (16)
 10 (15)
 NA
M. perstans infection 0.408‡
Yes 15 (100) NA 15 (23) 4 (13)
No 0 NA 51 (77) 26 (87)

*NA, not applicable.
†Comparison of combined M. ulcerans monoinfected and M. ulcerans co-infected with M. perstans versus household contacts, determined by 2-tailed Fisher exact test.
‡Comparison of M. ulcerans co-infected with M. perstans versus M. ulcerans monoinfected group, determined by 2-tailed Fisher exact test.

Main Article

Medline reports that reference 8 "Hoerauf, Specht, Buttner, Pfarr, Mand, Fimmers, et al., 2008" was corrected in "Med Microbiol Immunol. 2008 Sep;197(3):335" (Note: Taylor, Mark J [added]).

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Page updated: May 16, 2014
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