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Volume 21, Number 9—September 2015
THEME ISSUE
Emerging Infections Program

Use of Pneumococcal Disease Epidemiology to Set Policy and Prevent Disease during 20 Years of the Emerging Infections Program

Matthew R. MooreComments to Author  and Cynthia G. Whitney
Author affiliations: Centers for Disease Control and Prevention, Atlanta, Georgia, USA

Main Article

Table

Comparison of serotype-specific effectiveness of PCV7 (EIP/ABCs case–control study) (14) with that of NCKP trial (9) against invasive pneumococcal disease*

Serotype
Vaccine effectiveness/efficacy, % (95% CI)
CDC/ABCs
NCKP trial 2000
All PCV7 types Healthy: 96 (93–98); underlying illness: 81 (57–92) 94 (80–98)
4 93 (65–99) NA
6B 94 (77–98) 86 (−11 to 100)
9V 100 (88–100) 100 (−142 to 100)
14 94 (81–98) 100 (60–100)
18C 97 (85–99) 100 (49–100)
19F 87 (65–95) 85 (32–98)
23F 98 (80–100) 100 (15–100)

*PCV7, 7-valent pneumococcal conjugate vaccine; EIP, Emerging Infections Program; ABCs, Active Bacterial Core Surveillance; NCKP, Northern California Kaiser Permanente; CDC, Centers for Disease Control and Prevention; NA, not available.

Main Article

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Page created: August 12, 2015
Page updated: August 12, 2015
Page reviewed: August 12, 2015
The conclusions, findings, and opinions expressed by authors contributing to this journal do not necessarily reflect the official position of the U.S. Department of Health and Human Services, the Public Health Service, the Centers for Disease Control and Prevention, or the authors' affiliated institutions. Use of trade names is for identification only and does not imply endorsement by any of the groups named above.
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