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Volume 22, Number 10—October 2016
Letter

Cerebral Syphilitic Gumma within 5 Months of Syphilis in HIV-Infected Patient

Motoyuki Tsuboi, Takeshi NishijimaComments to Author , Katsuji Teruya, Yoshimi Kikuchi, Hiroyuki Gatanaga, and Shinichi Oka
Author affiliations: National Center for Global Health and Medicine, Tokyo, Japan (M. Tsuboi, T. Nishijima, K. Teruya, Y. Kikuchi, H. Gatanaga, S. Oka); Kumamoto University, Kumamoto, Japan (H. Gatanaga, S. Oka)

Main Article

Figure

Diagnostic imaging results for a brain mass in a 21-year-old HIV-positive man with cerebral syphilitic gumma in Tokyo, Japan, for whom serum samples obtained as recently as 5 months earlier showed negative results for syphilis. A) Noncontrast, cranial computed tomography showing a hypodense lesion in the left frontal lobe. B) Gadolinium-enhanced, axial, T1-weighted magnetic resonance imaging (MRI) showing an enhanced lesion (mass) (14 × 14 × 12 mm) adjacent to the enhanced dura in the left front

Figure. Diagnostic imaging results for a brain mass in a 21-year-old HIV-positive man with cerebral syphilitic gumma in Tokyo, Japan, for whom serum samples obtained as recently as 5 months earlier showed negative results for syphilis. A) Noncontrast, cranial computed tomography showing a hypodense lesion in the left frontal lobe. B) Gadolinium-enhanced, axial, T1-weighted magnetic resonance imaging (MRI) showing an enhanced lesion (mass) (14 × 14 × 12 mm) adjacent to the enhanced dura in the left frontal lobe. C) Axial, fluid-attenuated inversion recovery MRI showing extensive left frontal edema. D) Two months after treatment for syphilis, gadolinium-enhanced, axial T1-weighted MRI showing substantial resolution of the lesion.

Main Article

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