Volume 22, Number 11—November 2016
Dispatch
Capsular Switching and Other Large-Scale Recombination Events in Invasive Sequence Type 1 Group B Streptococcus
Figure

Figure. Extent of recombination among 8 non–serotype V sequence type (ST) 1 group B Streptococcus isolates collected by the Toronto Invasive Bacterial Diseases Network, Ontario, Canada, 2009–2015. A) Serotype Ib strain NGBS217. B) Serotype II strains NGBS748 and NGBS814. C) Serotype IV strain NGBS1098. D) Serotype VI strains NGBS209 and NGBS537. E) Serotype VII strain NGBS015. F) Serotype VIII strain NGBS621. Polymorphisms identified in non–serotype V ST1 strains (illustrated in different colors, with each line representing a polymorphism) are plotted against the genome sequence of reference serotype V ST1 strain SS1 (innermost circle). The cps locus is shown in gold in the outermost circle. Genome landmarks, such as genes used in the multilocus sequence typing scheme (adhP, atr, tkt, glcK, sdhA, glnA, and pheS) are shown in light blue. Mobile genetic elements of strain SS1 are depicted in black. Polymorphisms mapping to mobile genetic elements identified in the various non–serotype V ST1 strains were not included in the analysis. ST1, sequence type 1.