Volume 22, Number 11—November 2016
Dispatch
ESBL-Producing and Macrolide-Resistant Shigella sonnei Infections among Men Who Have Sex with Men, England, 2015
Figure 1
![Genomic plot of multidrug-resistance plasmid p183660 (inner ring, blue) from a man in England infected with Shigella sonnei compared with pKSR100 (outer ring, purple), a multidrug-resistance plasmid from a case of S. flexneri 3a infection occurring among men who have sex in men (4). Drug-resistant elements from p183660 are shown in red. Plot produced by using BLAST Ring Image Generator (5).](/eid/images/16-0653-F1.jpg)
Figure 1. Genomic plot of multidrug-resistance plasmid p183660 (inner ring, blue) from a man in England infected with Shigella sonnei compared with pKSR100 (outer ring, purple), a multidrug-resistance plasmid from a case of S. flexneri 3a infection occurring among men who have sex in men (4). Drug-resistant elements from p183660 are shown in red. Plot produced by using BLAST Ring Image Generator (5).
References
- Borg ML, Modi A, Tostmann A, Gobin M, Cartwright J, Quigley C, Ongoing outbreak of Shigella flexneri serotype 3a in men who have sex with men in England and Wales, data from 2009-2011. Euro Surveill. 2012;17:20137.PubMedGoogle Scholar
- Simms I, Field N, Jenkins C, Childs T, Gilbart VL, Dallman TJ, Intensified shigellosis epidemic associated with sexual transmission in men who have sex with men—Shigella flexneri and S. sonnei in England, 2004 to end of February 2015. Euro Surveill. 2015;20:21097.DOIPubMedGoogle Scholar
- Ashton P, Nair S, Peters T, Tewolde R, Day M, Doumith M, Revolutionising public health reference microbiology using whole genome sequencing: salmonella as an exemplar. bioRxiv. 2015;•••:033225.
- Baker KS, Dallman TJ, Ashton PM, Day M, Hughes G, Crook PD, Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study. Lancet Infect Dis. 2015;15:913–21.DOIPubMedGoogle Scholar
- Alikhan N-F, Petty NK, Ben Zakour NL, Beatson SA. BLAST Ring Image Generator (BRIG): simple prokaryote genome comparisons. BMC Genomics. 2011;12:402.DOIPubMedGoogle Scholar
- Gilbart VL, Simms I, Jenkins C, Furegato M, Gobin M, Oliver I, Sex, drugs and smart phone applications: findings from semistructured interviews with men who have sex with men diagnosed with Shigella flexneri 3a in England and Wales. Sex Transm Infect. 2015;91:598–602.DOIPubMedGoogle Scholar
- Baer JT, Vugia DJ, Reingold AL, Aragon T, Angulo FJ, Bradford WZ. HIV infection as a risk factor for shigellosis. Emerg Infect Dis. 1999;5:820–3.DOIPubMedGoogle Scholar
- Hoffmann C, Sahly H, Jessen A, Ingiliz P, Stellbrink H-J, Neifer S, High rates of quinolone-resistant strains of Shigella sonnei in HIV-infected MSM. Infection. 2013;41:999–1003.DOIPubMedGoogle Scholar
- Bowen A, Eikmeier D, Talley P, Siston A, Smith S, Hurd J, ; Centers for Disease Control and Prevention (CDC). Notes from the field: outbreaks of Shigella sonnei infection with decreased susceptibility to azithromycin among men who have Sex with men—Chicago and Metropolitan Minneapolis–St. Paul, 2014. MMWR Morb Mortal Wkly Rep. 2015;64:597–8.PubMedGoogle Scholar
- Public Health England. Shigella: leaflet and poster for men who have sex with men. 2013 Dec 1 [cited 2016 Feb 10]. https://www.gov.uk/government/publications/shigella-leaflet-and-poster
1These authors contributed equally to this article.
2These senior authors contributed equally to this article.
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