Volume 22, Number 6—June 2016
High MICs for Vancomycin and Daptomycin and Complicated Catheter-Related Bloodstream Infections with Methicillin-Sensitive Staphylococcus aureus
||Univariate, HR (95% CI)
||Multivariate, HR (95% CI)†
|Recruiting center 1||3.6 (1.6–8.1)||–|
|Any daptomycin-containing empiric therapy||2.5 (1.1–5.7)||–|
|Daptomycin monotherapy as empiric therapy||3.1 (1.3–7.1)||–|
|Vancomycin MIC >1.5 μg/mL||2.6 (1.1–5.9)||2.4 (1.2–5.5)|
|Daptomycin MIC >0.5 μg/mL||3.4 (1.6–8.2)||2.4 (1.1–5.9)|
*HR, hazard ratio; –, corresponding variables were not retained in the final model.
†Various models, including a maximum of 3 variables, were explored that combined all statistically significant variables identified at the univariate level. Only variables that were constantly retained in these models are shown with minimum HR values obtained.