Volume 22, Number 7—July 2016
Research
Tropheryma whipplei as a Cause of Epidemic Fever, Senegal, 2010–2012
Hubert Bassene, Oleg Mediannikov, Cristina Socolovschi, Pavel Ratmanov, Alpha K. Keita, Cheikh Sokhna, Didier Raoult, and Florence Fenollar
Table 1
Clinical manifestations observed in 786 febrile Tropheryma whipplei–positive or –negative patients in 2 villages, Dielmo and Ndiop in the Sine-Saloum area of Senegal, June 2010–March 2012.
| Clinical manifestation | T. whipplei–positive patients, no. (%), n = 36 | T. whipplei–negative patients, no. (%), n = 750 | p value by χ2 test |
|---|---|---|---|
| Headache | 23 (68.9) | 439 (58.5) | 0.52 |
| Arthralgia | 0 | 19 (2.5) | 0.46 |
| Myalgia | 0 | 53 (7.0) | 0.07 |
| Diarrhea | 3 (8.3) | 39 (5.2) | 0.3 |
| Vomiting | 4 (11.1) | 94 (12.5) | 0.56 |
| Nausea | 5 (13.9) | 100 (13.3) | 0.53 |
| Abdominal pain | 1 (2.8) | 21 (2.8) | 0.68 |
| Cough | 13 (36.1) | 274 (36.5) | 0.95 |
| Expectoration | 2 (5.6) | 42 (5.6) | 0.67 |
| Otalgia | 1 (2.8) | 28 (3.7) | 0.61 |
| Otorrhea | 0 | 2 (0.3) | 0.91 |
| Rhinorrhea | 8 (22.2) | 229 (30.5) | 0.28 |
| Burning urination | 1 (2.8) | 33 (4.4) | 0.53 |
| Rash | 0 | 10 (1.3) | 0.62 |
| Meningeal signs | 2 (5.5) | 25 (3.3) | 0.35 |
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