Volume 22, Number 7—July 2016
CME ACTIVITY - Synopsis
Current Guidelines, Common Clinical Pitfalls, and Future Directions for Laboratory Diagnosis of Lyme Disease, United States
Figure 3

Figure 3. Clinical approach to diagnosis of early Lyme disease, United States. *See Figure 1. †Given the gradual geographic expansion of Lyme disease, testing may be warranted for patients with signs and symptoms of Lyme disease who were exposed in areas that border known disease-endemic regions. ‡For a more detailed discussion of symptoms as they relate to pretest probability, see section on exposure and pretest probability. §For recommended 2-tiered testing protocol, see Figure 2. STARI, Southern tick−associated rash illness; EM, erythema migrans.
1These authors contributed equally to this article.