Hemolysis after Oral Artemisinin Combination Therapy for Uncomplicated Plasmodium falciparum Malaria
Florian Kurth
, Tilman Lingscheid, Florian Steiner, Miriam S. Stegemann, Sabine Bélard, Nikolai Menner, Peter Pongratz, Johanna Kim, Horst von Bernuth, Beate Mayer, Georg Damm, Daniel Seehofer, Abdulgabar Salama, Norbert Suttorp, and Thomas Zoller
Author affiliations: Charité–Universitätsmedizin Berlin, Berlin, Germany (F. Kurth, T. Lingscheid, F. Steiner, M.S. Stegemann, S. Bélard, N. Menner, P. Pongratz, J. Kim, H. von Bernuth, B. Mayer, G. Damm, D. Seehofer, A. Salama, N. Suttorp, T. Zoller); Swiss Tropical and Public Health Institute, Basel, Switzerland (T. Zoller)
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Figure 2
Figure 2. Changes in hemoglobin levels (ΔHb) for patients without posttreatment hemolysis, with compensated posttreatment hemolysis, and with uncompensated posttreatment hemolysis after treatment with oral artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria. A) day (d) 0 to d 14 (overall); B) d 0 to d 3 (treatment period); C) d 3 to d 14 (posttreatment period). Horizontal lines indicate median values, boxes indicate interquartile ranges, whiskers indicate ranges, and solid squares, circles, and triangles indicate individual patient data points.
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